Pabedil Tablet (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, take 12.5 mg of carvedilol orally once daily, followed by 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, take 12.5 mg of this medicine per dose orally twice daily, followed by 25 mg per dose orally twice daily. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If a dose increase is needed (excluding older adults), the dose may be increased to 50 mg per dose twice daily.

This medication should not be administered to certain patients. For example, patients who had allergic reactions to this drug or its components, patients with cardiogenic shock, patients with severe cardiac conduction disorders, patients with cor pulmonale, patients with metabolic acidosis due to diabetes, patients with severely weakened myocardium, patients with a history of respiratory diseases such as asthma or chronic obstructive pulmonary disease, patients with secondary hypertension, patients with certain heart conditions, pregnant or breastfeeding women, and patients with genetic issues such as lactose intolerance should not use this drug. Additionally, patients with diabetes, a history of allergic hypersensitivity reactions, a history of skin diseases caused by beta-blockers, patients with hypotension or renal failure, patients with unstable cardiac function, patients with severely reduced renal function, the elderly, and patients taking certain medications should use this drug with caution. This drug affects the central nervous system, which may cause dizziness, headache, and fatigue, and can rarely lead to hallucinations or mental disturbances. It can also impact the cardiovascular system, resulting in a slowed heart rate, heart failure, lowered blood pressure, or shock, necessitating regular cardiac function tests. In patients with impaired renal function, renal function may deteriorate, and respiratory disease patients may experience worsening dyspnea. Gastrointestinal symptoms such as nausea, diarrhea, and abdominal pain may occur. Skin reactions such as allergic rashes or itching, sweating, and abnormalities in blood or liver function have also been reported. This medication may complicate blood sugar control in diabetic patients, so blood sugar should be monitored regularly. Long-term use of this drug requires regular cardiac function tests and evaluations of liver and kidney function, especially because discontinuation should be done slowly under medical supervision, as abrupt cessation can worsen heart disease symptoms. Also, this drug may interact with other medications, so caution is needed when taken with antihypertensives, antidepressants, antiarrhythmics, insulin, and alcohol or grapefruit juice should also be avoided. Pregnant or breastfeeding women should not take this medication, and its safety has not been established in children or adolescents under 18 years old, so it is not recommended for this group. In the elderly, drug concentrations may increase due to reduced liver function, thus starting at a lower dose and careful administration is necessary. In case of overdose, severe hypotension, decreased heart rate, cardiac dysfunction, shock, and respiratory distress may occur, so immediate medical attention should be sought.

• dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication may be sensitive to light, so it should be stored in an airtight container that blocks light. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White circular tablet

Package unit

90 tablets/PTP[((10 tablets/PTP)x9)]