Cretap Tablet 5mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 milligrams once daily, and for patients requiring greater LDL cholesterol reduction, the maintenance dose can be adjusted accordingly. The maintenance dose is 10 milligrams once daily for most patients. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or longer, with a maximum increase to 20 milligrams daily.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the usual dosage range is 5 to 20 milligrams once daily. The dosage should be adjusted individually based on the recommended treatment goals for each patient.

This medication should not be used in certain patients. For example, it should not be administered to patients allergic to its components, those with severe liver impairment, patients with muscle disorders, patients taking specific concurrent medications, patients with severe renal impairment, or women who are pregnant or breastfeeding. Additionally, high-dose administration is prohibited in patients at high risk for muscle-related side effects. Since this medication contains lactose, patients with lactose intolerance should not take it. Regular monitoring of liver function and muscle status is necessary while taking this medication, especially if there is a history of excessive alcohol use or liver disease. If symptoms such as muscle pain, muscle weakness, or cramps occur, a doctor should be notified immediately, and in severe cases, discontinuation of the medication is required. In cases of acute severe illness or the onset of muscle weakness, the use of this medication should also be discontinued. There may be interactions with other medications, so any medications currently being taken should be reported to a doctor or pharmacist. Particularly, when combined with certain antiviral drugs, immunosuppressants, antibiotics, or fibrate class drugs, the risk of muscle side effects may increase. Women who may become pregnant should use adequate contraception, and those who are pregnant or breastfeeding should not take this medication. In case of overdose, there is no specific antidote, so treatment should be symptomatic, along with monitoring liver and muscle function. This medication generally does not significantly impair the ability to drive or operate machinery, but care should be taken as dizziness may occur. Lastly, this medication may result in higher systemic concentrations in Asians, so caution is needed in determining the dosage.

Serious side effects

Allergic reactions including urticaria and angioedema, severe swelling (edema), chest tightness, shortness of breath, cold sweat, paleness, severe allergic reactions, severe rash with fever, blisters, skin peeling, oral/eye mucosal pain, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanying cough and fever, jaundice (yellowing of the skin or eyes), and extreme lethargy; liver abnormalities

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• diarrhea
• rash

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best to store it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer time.

Appearance

Yellow round film-coated tablet

Package unit

28 tablets (14 tablets/PTP packaging x 2), 30 tablets/bottle