Medication info

Prilencapsule 25mg (Pregabalin)

Prescription medicationHard capsule경구Approval withdrawn
Ingredient · strength
Pregabalin›25mg / 1 capsule
Manufacturer / importer
(주)유앤생명과학
Appearance
A hard capsule with pale yellow upper part and white lower part containing white powder
Packaging
30 capsules/bottle
Approval status
Approval withdrawn

MFDS item code 202001439 · Approved 2020.02.29

This product's status changed to Approval withdrawn on 2025.02.27. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive treatment for epilepsy (partial seizures), improvement of fibromyalgia
Who takes it
Adults · Children
Adult dose
This drug should be taken orally as Pregabalin, divided into two doses per day, regardless of food intake. 1. Neuropathic Pain - Peripheral Neuropathic Pain: Starting dose is 150 mg per day, can be increased to 300 mg per day after 3 to 7 days, and can be further increased to a maximum of 600 mg at 7-day intervals if needed. - Central Neuropathic Pain: Starting dose is 150 mg per day, can be increased to 300 mg per day after one week
Child dose
Not recommended for children under 12 years of age and adolescents aged 12 to 17 due to insufficient safety and efficacy data

Ingredients

Manufacturer
(주)유앤생명과학

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive treatment for epilepsy (partial seizures), improvement of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This drug is used to treat peripheral and central neuropathic pain in adults. It is also utilized as an adjunctive treatment for partial seizures in adults, whether or not accompanied by secondary general symptoms. Additionally, it is effective in alleviating symptoms of fibromyalgia, thus aiding in the treatment of various neurological disorders.

How to take

Adult dose

This drug should be taken orally as Pregabalin, divided into two doses per day, regardless of food intake. 1. Neuropathic Pain - Peripheral Neuropathic Pain: Starting dose is 150 mg per day, can be increased to 300 mg per day after 3 to 7 days, and can be further increased to a maximum of 600 mg at 7-day intervals if needed. - Central Neuropathic Pain: Starting dose is 150 mg per day, can be increased to 300 mg per day after one week

Child dose

Not recommended for children under 12 years of age and adolescents aged 12 to 17 due to insufficient safety and efficacy data

Precautions

This drug may increase the risk of suicidal thoughts or behaviors, so changes in mood or symptoms of depression should be closely monitored during treatment. Patients with allergies to the components of this drug or those with specific genetic lactose degradation disorders should not take this drug. Diabetic patients may need to adjust the dosage of their blood glucose control medications due to potential weight gain after taking this drug. This drug can cause severe allergic reactions such as angioedema, so if swelling in the face or neck or difficulty breathing occurs, it should be discontinued immediately. Elderly patients may have an increased risk of falls due to dizziness or drowsiness when taking this drug, particularly during the initial dose. Temporary blurred vision or changes in vision may occur, and if symptoms persist, a consultation with a physician is advised. Withdrawal symptoms such as insomnia, headaches, and anxiety may occur upon discontinuation of this drug, so the dosage should be gradually reduced according to the physician's instructions. This drug has a risk of abuse, so patients with a history of substance abuse should take it with greater caution and notify their physician if any unusual behavior occurs. Patients with impaired kidney function may require dosage adjustment. Patients with heart disease or congestive heart failure should exercise caution while taking this drug. The risk of central nervous system depression may increase when used in combination with opioid analgesics, so a physician should be consulted. This drug may cause dizziness and drowsiness, so driving or operating hazardous machinery should be avoided after taking it. During early pregnancy, it may affect the fetus, so pregnant women are advised not to take it, and women of childbearing age should use effective contraception. Lactating women should consult with their physician regarding discontinuing breastfeeding or the drug, as this drug may be transmitted through breast milk. In the case of an overdose, symptoms such as confusion, drowsiness, and seizures may appear, necessitating an immediate visit to a medical institution. It should be kept out of reach of children and not transferred to other containers for safety. This drug has minimal drug interactions, but caution should be exercised when taken with other central nervous system depressants.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, high fever with severe rash, blisters, peeled skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, lightning headaches, seizures, confusion, vision abnormalities, paralysis, urination

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • disorientation
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • sexual dysesthesia
  • restlessness
  • anxiety
  • mood swings
  • emotional lability
  • difficulty finding the right words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulse control disorder
  • apathy
  • ataxia
  • abnormal coordinating movements
  • balance disorder
  • amnesia
  • attention deficit
  • memory impairment
  • tremors
  • speech disorders
  • sensory disturbances
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This drug may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 15 to 30 degrees Celsius.

Appearance and packaging

Appearance

A hard capsule with pale yellow upper part and white lower part containing white powder

Package unit

30 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.