Medication info
Levofloxacin 250 mg Tablets (Levofloxacin Hemihydrate)

Levofloxacin 250 mg Tablets (Levofloxacin Hemihydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›256.15mg / 1 tablet
Manufacturer / importer
건일바이오팜주식회사
Appearance
Light pink oval film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202001396 · Approved 2020.02.27 · Insurance code 073000740

Summary

Main use
Treatment of bacterial infections such as complicated skin and soft tissue infections, community-acquired pneumonia
Who takes it
Adults
Adult dose
For typical adult administration of levofloxacin, 250-750 mg is taken orally once daily. 1. Patients with normal renal function (creatinine clearance above 80 mL/min) - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10-14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbations of chronic bronchitis: for 7 days - Acute sinusitis: for 10-14 days - Chronic

Ingredients

Manufacturer
건일바이오팜주식회사

Efficacy & effects

Treatment of bacterial infections such as complicated skin and soft tissue infections, community-acquired pneumonia

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary tract infections
  • simple urinary tract infections
View approved original text

This medication is used to treat various infections caused by different bacteria. It targets several strains including Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, and is primarily used to treat complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, acute sinusitis, chronic bacterial prostatitis, and complicated urinary tract infections including acute pyelonephritis and simple cystitis. However, as a fluoroquinolone, it has the potential for serious adverse reactions, and it is recommended to use it only when no other treatment options are available for certain infections. Therefore, this drug is used cautiously for the treatment of various infections targeting important strains.

How to take

Adult dose

For typical adult administration of levofloxacin, 250-750 mg is taken orally once daily. 1. Patients with normal renal function (creatinine clearance above 80 mL/min) - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10-14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbations of chronic bronchitis: for 7 days - Acute sinusitis: for 10-14 days - Chronic

Precautions

This drug is used as a fluoroquinolone antibiotic for the treatment of several bacterial infections. Caution is advised when using this medication, as serious side effects such as tendon problems like tendonitis or tendon rupture, peripheral neuropathy, central nervous system effects, and worsening of myasthenia gravis can occur. Patients with myasthenia gravis should avoid using this medication as it could worsen their symptoms. This drug should only be used for certain infections such as acute bacterial rhinosinusitis, acute exacerbation of chronic bronchitis, simple urinary tract infections, and acute otitis media when no other treatment options are available, and it should be used with caution. Elderly patients, patients with impaired renal function, organ transplant recipients, and those using corticosteroids together have an increased risk of tendon rupture and should avoid use in combination with corticosteroids. This medication can cause seizures, so patients with epilepsy or central nervous system diseases should exercise particular caution, and use should be stopped immediately if seizures occur. It should not be administered to patients with a history of hypersensitivity to this drug or tendon problems caused by this drug, to children under 18 years of age, to pregnant or breastfeeding women, or to patients with epilepsy. Patients with very poor renal function, central nervous system diseases, elderly patients, and diabetic patients should consult a doctor before use for careful management. While taking this medication, symptoms such as hypotension, difficulty breathing, severe skin rashes, neuropsychiatric symptoms (anxiety, hallucinations, seizures), heart rhythm abnormalities, abnormalities in kidney and liver function, blood abnormalities, gastrointestinal disturbances, muscle and joint pain, and severe skin reactions may occur, and any abnormal symptoms should be reported to a healthcare professional immediately. Additionally, this drug may increase sensitivity to sunlight, so it is advisable to avoid strong sunlight or exposure to artificial UV rays. Dizziness or drowsiness may occur when driving or operating machinery, so caution is advised. This drug can interact with other medications, especially antacids, iron supplements, calcium supplements, anticoagulants, and antihyperglycemic agents, so it is essential to inform a doctor or pharmacist about any such medications and adjust the dosage accordingly. Pregnant or breastfeeding women should not use this drug, and if breastfeeding, it is recommended to discontinue breastfeeding. Children and adolescents should not be given this medication due to the risk of joint damage. Elderly patients may have elevated drug concentrations due to decreased renal function and are also at risk for liver toxicity, so careful monitoring and dosage adjustments are necessary. In case of overdose, central nervous system symptoms and cardiac abnormalities may occur, requiring immediate medical attention, as it cannot be removed by dialysis. This medication should only be taken for the minimum period necessary for treatment, and any adverse reactions or symptoms should be discussed with a healthcare professional immediately.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, tightness in the chest, difficulty breathing, cold sweat, pallor (severe allergic reaction), high fever with severe rash, blisters, skin peeling, pain in mucous membranes (severe skin adverse reaction), difficulty breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever (respiratory issue), yellowing of the skin or eyes (jaundice), extreme fatigue (liver issue), sudden and severe headache

Mild side effects

Nausea, diarrhea, vaginitis, insomnia, abdominal pain, bloating, itching, dizziness, rash, dyspepsia, stomatitis, glossitis, dry mouth, constipation, vomiting, genital itching, headache, neurotic symptoms, erythematous rash, hives, decreased appetite, drowsiness, agitation, thirst, tremors, allergic reactions, neuropsychiatric symptoms (anxiety, depression, hallucinations, paranoia, irritability, delirium, disorientation, attention deficit, nightmares, sleep disorders, suicidal thoughts,

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly sealed container to protect it from air and moisture and should be kept at room temperature between 1°C and 30°C. Avoid direct sunlight and extremes of temperature to help maintain the drug's effectiveness.

Appearance and packaging

Appearance

Light pink oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.