K-Sillin Duo Syrup [Amoxicillin-Potassium Clavulanate (7:1)]

Adult dose

For moderately severe infections such as recurrent tonsillitis, upper respiratory infections, lower respiratory infections, urinary tract infections, and skin and soft tissue infections, take 25 mg/3.6 mg per kg of body weight divided into two doses per day. For severe infections such as otitis media and sinusitis, as well as lower respiratory infections like bronchopneumonia and urinary tract infections, take 45 mg/6.4 mg per kg of body weight divided into two doses per day. To minimize the potential gastrointestinal intolerance, it is advised to administer at the beginning of meals.

Child dose

The 7:1 syrup is not suitable for infants under 2 months. Pediatric patients with renal failure are not suited for the 7:1 syrup.

This medication contains the artificial sweetener aspartame, and should not be used in patients with the genetic disorder phenylketonuria. The daily intake of aspartame is restricted based on body weight, so the minimum amount possible should be used. Patients who have had hypersensitivity reactions to this drug's components or to beta-lactam antibiotics should not take this medication. Patients with infectious mononucleosis or lymphocytic leukemia should be cautious due to the risk of rash. Patients with a history of liver dysfunction or jaundice may have a risk of recurrence upon use of this drug and should avoid it. This medication contains lactose and should not be administered to patients with lactose intolerance or related genetic disorders. Patients with impaired liver or kidney function should carefully consider dosage adjustments and administration intervals when using this drug. Patients with allergies or gastrointestinal diseases are at increased risk for side effects and require careful monitoring. If any abnormal symptoms such as diarrhea, abdominal pain, or rash occur during use, they should consult a doctor immediately. Serious side effects such as pseudomembranous colitis due to antibiotic use may occur; therefore, this medication should be discontinued immediately upon symptom onset. Regular checks for resistance bacteria and abnormalities in liver and kidney function are important during long-term use. This medication may interact with other drugs, so inform healthcare providers of any other medications being taken. Women who are pregnant or nursing should carefully assess the benefits and risks of using this drug, especially during early pregnancy. The safety of this medication has not been established in children, particularly neonates under 2 months of age, and caution is advised. Elderly individuals are at higher risk of side effects due to decreased physical function and should use this drug with dosage and administration intervals adjusted carefully. This medication should be stored in a refrigerator and used within 7 days after preparation. In case of overdose, gastrointestinal symptoms or allergic reactions may occur; therefore, immediate medical attention should be sought.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, anaphylaxis, Stevens-Johnson syndrome, shock, severe allergic reactions, high fever accompanied by severe rash, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough + fever, jaundice, generalized lethargy.

Mild side effects

Diarrhea, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal distension, constipation, colonic pain, hyperacidity, soft stool, dry mouth, elevated AST, elevated ALT, elevated ALP, elevated LDH, increased serum bilirubin, hepatitis, cholestatic jaundice, itching, erythema multiforme, skin rash, angioedema, serum sickness-like syndrome, hypersensitivity vasculitis, acute generalized exanthematous pustulosis, bronchospasm.

This medication should be stored in a tightly sealed container to protect it from air and moisture, maintaining a storage temperature between 1 to 25 degrees Celsius. Therefore, it is important to keep the medication in a cool and dry place until it is used.

Appearance

A whitish powder with a peculiar smell, a syrup that dissolves prior to use.

Package unit

50 milliliters/bottle