Medication info
Lurucapsule 25 mg (Pregabalin)

Lurucapsule 25 mg (Pregabalin)

Prescription medicationHard capsule
Ingredient · strength
Pregabalin›25mg / 1 capsule
Manufacturer / importer
(주)중헌제약
Appearance
A hard capsule with a light yellow upper part and white lower part containing a powder that is white to light yellow.
Packaging
30 capsules/bottle
Approval status
Active

MFDS item code 202000173 · Approved 2020.01.10 · Insurance code 053301110

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, improvement of fibromyalgia.
Who uses it
Adults · Children
Adult dosage
This medication is taken orally, divided into two doses per day, regardless of food. 1. Neuropathic Pain 1) Peripheral Neuropathic Pain - Starting dose: 150 mg/day - Increase to a maximum of 300 mg/day after 3-7 days - If necessary, further increase to a maximum of 600 mg/day every 7 days 2) Central Neuropathic Pain - Starting dose: 150 mg/day - Increase to 300 mg/day after one week
Children's dosage
Safety and efficacy data for children under 12 years and adolescents aged 12-17 are insufficient, so administration is not recommended.

Ingredients

Manufacturer
(주)중헌제약

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used to treat peripheral and central neuropathic pain in adults. It is also used as an adjunct in patients with epilepsy who have partial seizures, regardless of the presence of secondary systemic symptoms. Additionally, it is effective for the treatment of fibromyalgia. In other words, this medication is used to alleviate and treat various neurological symptoms and disorders.

Dosage and Administration

Adult dosage

This medication is taken orally, divided into two doses per day, regardless of food. 1. Neuropathic Pain 1) Peripheral Neuropathic Pain - Starting dose: 150 mg/day - Increase to a maximum of 300 mg/day after 3-7 days - If necessary, further increase to a maximum of 600 mg/day every 7 days 2) Central Neuropathic Pain - Starting dose: 150 mg/day - Increase to 300 mg/day after one week

Children's dosage

Safety and efficacy data for children under 12 years and adolescents aged 12-17 are insufficient, so administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so it is necessary to carefully monitor for changes in mood or unusual behavior during treatment. Patients with allergies to any component of this medication or those with genetic lactose intolerance should not take it. Diabetic patients may need to adjust their blood glucose-controlling medications due to weight gain. If symptoms of angioedema occur, the medication should be immediately discontinued and medical advice sought. Elderly patients should be cautious as the use of this medication may increase the risk of dizziness or sedation, which can lead to falls or injuries. Visual disturbances or changes in eyesight may occur, and should these symptoms arise, consideration should be given to discontinuing the medication. Suddenly stopping this medication may lead to withdrawal symptoms such as insomnia, headache, nausea, and anxiety, so dosage adjustments should be discussed with a healthcare provider. There is a risk of drug abuse; therefore, patients with a history of substance abuse should be particularly cautious. Patients with impaired kidney function may require dosage adjustments. Patients with heart disease may be at risk for heart failure while taking this medication and should use it carefully. When taken with opioid analgesics, the central nervous system depressive effects may be intensified, so caution is advised. Patients with weak respiratory function or elderly individuals may face a risk of severe respiratory depression and require dosage adjustments. In early pregnancy, there may be a risk of fetal malformation, so pregnant women are advised not to take it, and women of childbearing potential should use effective contraception. Breastfeeding women should be aware that this medication may be passed through breast milk and should consult with their healthcare provider about stopping breastfeeding or the medication. When engaging in activities that require alertness, such as driving or operating machinery, caution should be exercised as dizziness or sedation may occur due to this medication. Severe skin reactions may rarely occur, and if any skin abnormalities develop, the medication should be immediately discontinued and a healthcare provider notified. In case of overdose, symptoms such as confusion, drowsiness, and depression may occur, and treatment such as dialysis may be necessary. Special caution and dosage adjustments are required for children, the elderly, and patients with kidney disease. The medication should be stored out of reach of children and should not be transferred to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision abnormalities, paralysis, urination

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • impaired sense of direction
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • hyperesthesia
  • restlessness
  • anxiety
  • mood fluctuations
  • emotional lability
  • difficulty finding appropriate terms
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • coordination disturbance
  • balance disorders
  • amnesia
  • attention deficits
  • memory impairment
  • tremors
  • dysarthria
  • sensory disturbances
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best stored at room temperature between 15 to 30 degrees Celsius.

Appearance and packaging

Appearance

A hard capsule with a light yellow upper part and white lower part containing a powder that is white to light yellow.

Package unit

30 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.