Mega-Clarithin 500 mg (Clarithromycin)

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7 ∼ 14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer this medicine 500mg (potency) 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1 ∼ 14), and omeprazole 40mg once daily for 28 days (days 1 ∼ 28).

Children's dosage

Children aged 12 years and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, patients who are allergic to any ingredients in this medication or have a history of allergy to similar classes of antibiotics should not take this medication. Additionally, patients with specific heart conditions or severely impaired liver or kidney function should avoid using this medication. Women who are pregnant or breastfeeding should not take this medication. This medication may influence heart rhythms; therefore, patients with heart-related diseases or those taking specific medications should use it cautiously. During the course of taking this medication, allergic reactions, severe gastrointestinal disturbances, respiratory difficulties, skin rashes, or other unusual symptoms may occur. If any such symptoms arise, discontinue use immediately and consult a healthcare professional. Since this medication may affect liver and kidney functions, patients with liver or kidney disease should have regular check-ups and monitor their condition. Interactions with other medications could potentially exacerbate side effects, so it is important to notify healthcare professionals of all currently taken medications and manage them carefully. Older adults and children may require dosage adjustments or caution based on physical function. Long-term use of this medication may lead to drug resistance; therefore, taking it only for the prescribed duration under a doctor's guidance is crucial. Overdosing may lead to gastrointestinal disturbances or neurological symptoms; thus, strict adherence to the prescribed dose is necessary, and in the case of an overdose, immediate medical attention should be sought. Lastly, while taking this medication, dizziness or confusion may occur during driving or machine operation, so caution is advised.

Shock, anaphylactic symptoms, breathing difficulties, spasms, redness, rash, itching, hives, skin redness, vascular edema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, indigestion, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, spasmodic form, dry mouth, tooth discoloration, pancreatitis, increased amylase, dysgeusia, decreased appetite, constipation, discoloration of stools, pseudomembranous colitis, hemorrhagic colitis, abdominal pain, frequent diarrhea, fever, cough, breathing difficulties, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrate, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychiatric disorders, depersonalization, spasms, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, hepatic dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, decreased appetite, jaundice, dark urine, itching, abdominal tenderness, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, increased myoglobin in serum, increased myoglobin in urine, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorders, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute generalized exanthematous pustulosis, rash, hyperhidrosis, vesicular dermatitis, itching, hives, papular rash, acne, Henoch-Schonlein purpura, muscle cramps, musculoskeletal stiffness, myalgia, myopathy, elevated serum creatinine, increased blood urea, renal failure, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, increased serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urine color abnormalities, gastrointestinal symptoms, changes in mental administration, obsessive behavior, hypokalemia, hypoxemia

This medication is sensitive to light; thus, it should be stored in a container that is not transparent to light. Additionally, it is recommended to store it at room temperature between 15 degrees and 30 degrees Celsius. Storing it this way helps to maintain the effectiveness of the medication.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle