Carvedilol Tablets 25 mg (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor’s instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients In some elderly patients, 12.5 mg once daily may be sufficiently effective. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient’s existing standard treatment regimen (the conventional treatment regimen for chronic heart failure, consisting of an ACE inhibitor, a diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial treatment is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take the medicine with meals in the morning and evening. Taking it with meals slows absorption and may reduce the incidence of orthostatic hypotension.

This drug should not be used in patients with certain diseases or conditions. For example, it may be dangerous for patients with allergies to this drug or its components, cardiac shock, severe bradycardia, or cardiac conduction disorders. It should also not be administered to patients with cor pulmonale, diabetic ketoacidosis, severely weakened heart function, or respiratory diseases such as asthma or chronic obstructive pulmonary disease. Pregnant or breastfeeding women, patients with severe liver dysfunction, and patients with peripheral circulation disorders should also preferably not use this drug. Careful use is required in patients with diabetes, a history of hypersensitivity, heart diseases, or impaired kidney function. Symptoms such as dizziness, headache, and fatigue may occur during treatment, and it may cause a slow heart rate or low blood pressure, so regular cardiac function tests should be conducted. Additionally, liver or kidney function abnormalities may arise, requiring periodic testing, and if severe side effects occur, medical consultation should be sought immediately. This drug may interact with other medications; therefore, it is essential to inform healthcare providers of any other medications being taken. Particular caution is needed when used in conjunction with antihypertensives, antiarrhythmics, antidiabetic medications, and some antidepressants. Pregnant or breastfeeding women should not take this medication, and safety has not been established for children or adolescents under 18 years of age. Older adults may experience increased drug concentrations due to decreased liver function, and there is a risk of excessive blood pressure reduction leading to stroke, so treatment should start at a lower dose and be administered cautiously. In cases of overdose, symptoms such as bradycardia, hypotension, respiratory distress, or consciousness disorder may appear, necessitating immediate medical attention. This drug is sensitive to light and should be stored in a light-resistant container, out of the reach of children. Additionally, users must not arbitrarily discontinue or adjust the dosage and should follow their doctor's instructions.

• Dizziness
• headache
• fatigue
• weakness
• hallucination
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This drug is sensitive to light and should be stored in a special container that prevents exposure to light. It is also crucial to store it at room temperature, between 1 and 30 degrees Celsius, to maintain its efficacy.

Appearance

White round tablet

Package unit

90 tablets (10 tablets/PTP X 9)