Lobakay Tablet 20 mg (Rosuvastatin Calcium)

Adult dosage

Administer 5 mg once daily as the starting dose at any time of the day, regardless of meals. The maintenance dose is 10 mg once daily, and it can be adjusted to a maximum of 20 mg once daily based on patient response at an interval of 4 weeks or more.

Children's dosage

For pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, administer 5 mg to 20 mg once daily and adjust the dosage according to individual treatment goals with at least a 4-week interval.

This medication should not be administered to certain patients. For example, it should not be given to patients who are allergic to any component of this medication, those with severely impaired liver function, patients with muscle disorders, and those with severe renal impairment. Additionally, pregnant or breastfeeding women and women of childbearing age who do not use appropriate contraception should not use this medication. This medication can affect muscles, so caution is necessary for patients at high risk of muscle pain or myopathy. Especially at high doses, the risk of muscle damage increases, making dose adjustment important. Patients with liver dysfunction or those who consume excessive alcohol should have liver function tests before taking this medication and periodically monitor liver function during treatment. During treatment with this medication, if muscle pain, muscle weakness, or unexplainable fatigue or fever appear, inform medical personnel immediately. If these symptoms are severe or if blood tests indicate significantly elevated muscle damage markers, discontinuation of the medication may be warranted. This medication can interact with certain drugs when taken together, so if other medications are being taken, healthcare providers must be informed. Particularly, caution is needed when used in combination with drugs that increase the risk of muscle toxicity. Pregnant or breastfeeding women should not use this medication, and women of childbearing age should use appropriate contraception methods. In cases of overdose, there is no specific antidote available, so treatment should be symptomatic and liver function and muscle damage markers should be tested. This medication does not significantly impact driving or machinery operation abilities but caution is needed due to potential dizziness. Finally, during treatment with this medication, liver function and muscle health should be regularly monitored, and if abnormal symptoms appear, healthcare providers should be consulted immediately.

Serious side effects

Allergic reactions including hives and angioedema, chest tightness, difficulty breathing, severe swelling (edema), Stevens-Johnson syndrome, eosinophilia and systemic symptom drug reaction syndrome (DRESS), jaundice, hepatitis, increased transaminases, acute renal failure, oliguria, increased serum creatinine, severe myopathy (including myositis), rhabdomyolysis, immune-mediated necrotizing myopathy, severe muscle weakness, ophthalmoplegia

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• thrombocytopenia
• diarrhea

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Additionally, it is recommended to store the medication at room temperature between 1°C and 30°C. This helps maintain the drug's effectiveness over time.

Appearance

Pink, round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle