Aiclary Tablet 250mg (Clarithromycin)

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this drug to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this drug twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Helicobacter pylori eradication in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this drug three times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

○ Children 12 years of age and older: Same as adults. ○ Children under 12 years of age: Use clarithromycin dry syrup.

This medication should not be administered to patients with certain allergic reactions or with specific heart diseases, liver disorders, or kidney disorders. Additionally, patients taking certain medications may experience interactions with this drug, so it is essential to consult a physician or pharmacist before use. It is considered safe not to administer this drug to pregnant or breastfeeding women, and caution should be exercised when using it in children or elderly patients. During treatment, symptoms such as allergic reactions, gastrointestinal disturbances, skin rashes, liver function abnormalities, kidney function abnormalities, and central nervous system disturbances may occur, so any unusual symptoms should be reported to healthcare personnel immediately. Furthermore, this drug has many interactions with other medications, and the risk of side effects may increase when combined with some drugs, so it should be taken strictly according to medical advice. In cases of overdose, gastrointestinal symptoms or psychiatric symptoms may occur, and immediate emergency treatment is required. To prevent the development of resistant bacteria, it is important to use this drug only for the necessary duration after susceptibility testing. If persistent diarrhea or abdominal pain occurs during treatment, it may be a sign of serious side effects such as pseudomembranous colitis, so treatment should be stopped immediately and consulted with healthcare personnel. Caution is necessary while driving or operating machinery, as dizziness or confusion may occur. It is recommended to have regular liver function, kidney function, and blood tests to monitor for any abnormalities during the course of taking this medication.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral ulceration, upper abdominal pain, spasmodic upper abdominal pain, dry mouth, transient tooth discoloration, pancreatitis, increased amylase, taste disturbances, loss of appetite, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, exacerbation of chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, derealization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, increased total bilirubin, increased serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbances, tinnitus, auditory impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute generalized pustular dermatosis, soft tissue infection, candidiasis, gastroenteritis, infection, vaginal infection, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactic reaction, angioedema, loss of appetite, appetite decrease, hypoglycemia, insomnia, anxiety, irritability, noise sensitivity, psychotic disorders, confused state, derealization, depression, disorientation, hallucinations, abnormal dreams, mania, taste disturbances, headache, loss of consciousness, movement disorders, non-vestibular dizziness, drowsiness, tremor, vestibular dizziness, auditory impairment, hearing loss, cardiac arrest, atrial fibrillation, ECG QT prolongation, extrasystoles, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, diarrhea, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, abnormal liver function tests, cholestasis, hepatitis, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated gamma-glutamyl transferase, liver failure, hepatocellular jaundice, rash, hyperhidrosis, vesicular dermatitis, papulovesicular rash, acne, Henoch-Schonlein purpura, muscle cramps, musculoskeletal rigidity, myopathy, increased blood urea, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated alkaline phosphatase, elevated lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, changes in mental status, obsessive behavior, hypokalemia, hypoxemia

This medication is sensitive to light and should be stored in a container that protects it from light. Additionally, it is best to store the medication at room temperature between 15 degrees Celsius and 30 degrees Celsius, avoiding extremely hot or cold conditions.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 200 tablets/bottle