Curamuz 625 mg Tablet (Amoxicillin-Potassium Clavulanate)

Adult dose

For adults and children over 12 years or weighing more than 40 kg, Amoxicillin/Potassium Clavulanate is administered orally as a single dose of 250 mg/125 mg three times a day every 8 hours. In cases of severe and respiratory infections, the dose may be increased to 500 mg/125 mg once. For those with renal impairment, the dosage should be adjusted according to creatinine clearance, and for patients with a creatinine clearance of more than 30 mL/min, dosage adjustment is not required.

Child dose

For children under 12 years of age or weighing less than 40 kg, the dosage is adjusted and administered using the same method as adults.

This medicine is a beta-lactam antibiotic and should not be administered to patients with a history of hypersensitivity to penicillin or cephalosporin drugs. Patients with concomitant viral infections such as infectious mononucleosis or lymphocytic leukemia may have an increased risk of rash, so caution is needed. Patients who have had liver dysfunction or jaundice due to this medication or penicillin in the past should avoid its use due to the possibility of recurrence. Patients with poor liver function or severe kidney impairment may have elevated drug concentrations, so dosing intervals should be adjusted or used with caution. Those with allergic tendencies or family histories, and patients who have difficulty swallowing, elderly patients, or patients in poor overall condition are at risk of bleeding due to vitamin K deficiency, so caution is warranted. Patients with gastrointestinal diseases accompanied by vomiting or diarrhea may not absorb the medication properly, so careful administration is required. This medication can cause gastrointestinal adverse reactions such as diarrhea, dyspepsia, and vomiting, and in severe cases, pseudomembranous colitis or acute pancreatitis can occur. If symptoms develop, consult a physician immediately. Liver function abnormalities may also occur, which are reported more frequently in elderly patients over 60 years of age and males, so regular liver function tests should be conducted. Severe skin rashes and hypersensitivity reactions like anaphylaxis can occur infrequently; if symptoms such as skin rash, itching, or breathing difficulties occur, administration should be stopped immediately and healthcare personnel notified. Blood tests may rarely show abnormalities such as leukopenia or thrombocytopenia, so regular blood testing is necessary during long-term use. Central nervous system symptoms like anxiety, confusion, and seizures can rarely occur, so if any symptoms arise, a physician's evaluation is needed. Patients with impaired kidney function are at risk for acute renal failure or interstitial nephritis, so kidney function should be monitored regularly, and if abnormalities occur, administration should be discontinued. The use of antibiotics can alter the normal intestinal flora, potentially leading to oral candidiasis or candidiasis infections; consult a physician if symptoms arise. Vitamin K deficiency can lead to bleeding tendencies and vitamin B complex deficiencies may rarely occur, so nutritional status should be assessed with long-term use. This medication should be administered only for the necessary minimum duration after sensitivity testing to prevent resistance development. Patients with a history of hypersensitivity to penicillin drugs may experience severe allergic reactions, so they must inform the healthcare personnel before administration. There is a risk of anaphylaxis, so the patient's condition should be closely monitored for a period after administration. Long-term or excessive use may show gastrointestinal symptoms, bleeding, and hypersensitivity reactions; if symptoms arise, stop administration immediately and seek appropriate treatment. Administration should be avoided during the first three months of pregnancy, and pregnant or breastfeeding women should use this medication cautiously since it may affect the fetus or infant. This medication is not recommended for children under 12 years of age or those weighing less than 40 kg, and elderly patients may present more pronounced adverse reactions due to decreased physiological function, so dosages and intervals should be adjusted accordingly. This medication may interact with other medications, so if the patient is taking any other medications, it is crucial to inform the healthcare personnel. Store at or below 25 degrees in a dry place, and if any abnormal symptoms occur during use, consult a physician immediately.

Serious side effects

Hives, severe swelling (Angioedema), chest tightness, difficulty breathing, cold sweat, paleness, anaphylaxis, Stevens-Johnson syndrome, shock, severe rash, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing, asthma attacks, respiratory dysfunction accompanied by cough and fever, jaundice of the skin or eyes, extreme fatigue throughout the body, sudden and severe headache, thunderclap headache, seizures, loss of consciousness

Mild side effects

Diarrhea, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, black hairy tongue, nausea, vomiting, anorexia, abdominal pain, abdominal bloating, constipation, colonic pain, gastric acid increase, soft stools, dry mouth, acute pancreatitis, candidiasis, antibiotic-associated colitis, itching, erythema multiforme, dermatitis, blood system abnormalities (leukopenia, thrombocytopenia, hemolytic anemia, etc.), vaginal itching and increased secretions, restlessness, anxiety, behavioral changes, confusion,

This medicine is contained in a sealed container that protects it from air and moisture and should be stored in a dry place at or below 25 degrees. Storing it this way will help maintain the effectiveness of the medication for a longer time.

Appearance

This medicine is a white or almost white oval film-coated tablet.

Package unit

For oral use - 40 tablets/PTP [4 tablets/PTP * 10], For oral use - 60 tablets/PTP [6 tablets/PTP * 10]