Cephaclam Capsule (Cefaclor Hydrate)

Adult dosage

As cefaclor, administer 250mg (based on potency) orally every 8 hours. In cases of severe infections (such as pneumonia) and low-sensitive infections, the dosage may be doubled. For acute gonococcal urethritis, this medication is administered in a single dose of 3g along with probenecid 1g.

Children's dosage

Administer 20mg (based on potency) per kg of body weight divided into doses every 8 hours. In cases of severe infections, otitis media, and low-sensitive infections, it may be administered at 40mg (based on potency) per kg of body weight, with a maximum dosage of

This medication should not be administered to certain patients. For instance, individuals who have previously experienced severe allergic reactions or shock due to this medication, or those who are allergic to this medication or similar classes of antibiotics, should not use it. Additionally, because it contains lactose, patients with lactose intolerance or specific genetic metabolic disorders should not take it. This medication should be used cautiously in certain situations, particularly for individuals allergic to penicillin antibiotics or those with asthma or skin rashes, as they may have heightened sensitivity. Special monitoring is required for patients with severely impaired kidney function, the elderly, or those in poor overall health when taking this medication. While taking this medication, various side effects may occur such as rare instances of shock, anaphylaxis, skin disorders, blood abnormalities, liver or kidney dysfunction, gastrointestinal issues, respiratory problems, and neurological anomalies. If any of these symptoms arise, it is essential to discontinue the medication immediately and consult healthcare professionals. To prevent the emergence of resistant bacteria, it is important to confirm the sensitivity of the infecting bacteria and to take the medication for the minimum necessary duration. Caution should be exercised when taking this medication with other drugs as interactions may occur, particularly with probenecid, antacids, medications that affect the kidneys, anticoagulants, and oral contraceptives. Pregnant or breastfeeding women should only take this medication when absolutely necessary, as the safety during pregnancy has not been fully established, and care should be taken to consider the potential effects on the infant during breastfeeding. The safety for infants under 1 month old has not been established, and some formulations have not been sufficiently validated for efficacy and safety in children. Elderly patients may have reduced bodily functions and a higher risk of side effects, necessitating careful observation and adjustments to dosage and administration intervals. This medication may affect certain clinical test results, so patients should inform healthcare professionals about this prior to testing. In case of overdose, symptoms such as nausea, vomiting, abdominal discomfort, and diarrhea may occur, and in severe cases, treatment may be necessary to cleanse the stomach or reduce drug absorption. This medication is an antibiotic that exerts a bactericidal effect by inhibiting bacterial cell wall synthesis, thus requiring proper usage and precautions.

Serious side effects

Shock, urticaria, edema, dyspnea, vascular edema, symptoms of anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis, jaundice, acute renal failure, seizures, severe headache, altered consciousness, visual disturbances, paralysis, asthma attacks, dyspnea, elevated blood pressure, severe edema, severe colitis accompanied by bloody stools, severe renal impairment, interstitial pneumonia, eosinophilic pulmonary infiltration

Mild side effects

• General flushing
• sensory disturbances
• syncope
• hypertension
• vasodilation
• rash
• erythema
• itching
• fever
• lymphadenopathy

This medication is sensitive to light; therefore, it must be stored in a container that protects it from light. In addition, it is important to maintain a room temperature between 1 and 30 degrees Celsius during storage. Proper storage will help maintain the medication's effectiveness and safety over time.

Appearance

A hard capsule with a blue opaque upper part and a white opaque lower part filled with a light yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle