Medication info
Carvedilol Tablets 25 mg (Carvedilol)

Carvedilol Tablets 25 mg (Carvedilol)

Prescription medicationTabletOral
Ingredient · strength
Carvedilol›25mg / 1 tablet
Manufacturer / importer
Geonil Biopharm Co., Ltd.
Appearance
White round tablets
Packaging
90 tablets/box [(10 tablets/PTP×9)]
Approval status
Active

MFDS item code 201907208 · Approved 2019.10.14 · Insurance code 073000390

Summary

Main use
Treatment of essential hypertension and chronic stable angina; adjunctive treatment of congestive heart failure
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without your doctor's instructions. Essential hypertension Adults For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. Elderly patients In some elderly patients, 12.5 mg once daily may provide sufficient effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. Chronic stable angina For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard treatment regimen (conventional treatment for chronic heart failure with an ACE inhibitor, diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase to 12.5 mg twice daily for 2 weeks, and then increase to 25 mg twice daily. Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose tolerated by the patient. The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. To control the rate of absorption, it is recommended to take the medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Ingredients

Manufacturer
Geonil Biopharm Co., Ltd.

Efficacy & effects

Treatment of essential hypertension and chronic stable angina; adjunctive treatment of congestive heart failure

  • Essential hypertension
  • chronic stable angina pectoris
  • congestive heart failure
View approved original text

This medicine is used to treat essential hypertension, chronic stable angina pectoris, and congestive heart failure. It is particularly effective when administered together with diuretics, digitalis preparations, ACE inhibitors, or other vasodilators to enhance therapeutic effects. Therefore, it is effective in controlling blood pressure and improving cardiac function.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. Essential hypertension Adults For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. Elderly patients In some elderly patients, 12.5 mg once daily may provide sufficient effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. Chronic stable angina For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard treatment regimen (conventional treatment for chronic heart failure with an ACE inhibitor, diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase to 12.5 mg twice daily for 2 weeks, and then increase to 25 mg twice daily. Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose tolerated by the patient. The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. To control the rate of absorption, it is recommended to take the medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Precautions

This medication should not be used in certain patients. For example, individuals who are allergic to this drug or its components, those with severely compromised heart function, very slow heart rates, heart diseases related to the lungs, metabolic disorders due to diabetes, severe heart failure, asthma or chronic pulmonary disease, pregnant or breastfeeding women may be at risk when taking this medication. Additionally, patients with diabetes, those sensitive to allergic reactions, low blood pressure, impaired kidney function, and elderly individuals should exercise special caution when using this medication. In such cases, it should be taken carefully under the guidance of a physician. When taking this medication, symptoms such as dizziness, fatigue, and headache may occur, and heart rates may slow down or blood pressure may drop too low. In severe cases, heart failure may worsen or side effects such as difficulty breathing or skin rashes may occur, so it is important to consult a doctor if any abnormal symptoms appear. For long-term use, regular checks of heart function, blood pressure, and liver and kidney function should be conducted, and if suddenly discontinued, symptoms of heart disease may worsen, so dosage should be gradually reduced under a doctor’s guidance. This medication can interact with other drugs, so it is important to inform your physician or pharmacist if you are taking other antihypertensives, diabetes medications, heart medications, antidepressants, sedatives, etc. Particularly, when undergoing anesthesia or surgery, it is crucial to inform medical personnel about the use of this medication. Pregnant or breastfeeding women should not take this medication, and children or adolescents under 18 should avoid use as safety and effectiveness have not been established. In case of overdose, symptoms such as low blood pressure, arrhythmias, difficulty breathing, and consciousness disorders may present, so it is important to seek immediate medical treatment.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucinations
  • confusion
  • depression
  • sleep disturbances
  • nightmares
  • psychosis
Show 60 more
  • severe bradycardia
  • shock
  • complete atrioventricular block
  • heart failure
  • cardiac arrest
  • hypotension
  • loss of consciousness
  • reduced pulse rate
  • cold limbs
  • edema
  • asystole
  • worsening renal function
  • renal failure
  • increased airway resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichenoid reactions
  • sweating
  • allergic rash
  • serum aminotransferase changes
  • thrombocytopenia
  • leukopenia
  • hypoglycemia
  • masking of hyperthyroidism
  • hyperglycemia
  • weight gain
  • increased serum cholesterol
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension in angina
  • liver dysfunction
  • jaundice
  • limb pain
  • decreased tear production
  • sensory disturbances
  • visual disturbances
  • eye irritation
  • dry mouth
  • urination disorders
  • sexual dysfunction
  • allergic reactions
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • blood pressure lowering
  • decreased heart rate
  • myocardial weakness
  • cardiogenic shock
  • asystole
  • cardiac arrest
  • dyspnea
  • bronchospasm
  • vomiting
  • consciousness disturbances
  • tonic-clonic seizures

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that blocks light. It is also recommended to store the medication at room temperature, between 1 and 30 degrees Celsius. This will help maintain the medication's effectiveness and safety.

Appearance and packaging

Appearance

White round tablets

Package unit

90 tablets/box [(10 tablets/PTP×9)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.