Carvedilol Tablet 12.5 mg (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients In some elderly patients, 12.5 mg once daily may provide sufficient effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard treatment regimen (conventional treatment for chronic heart failure with an ACE inhibitor, diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase to 12.5 mg twice daily for 2 weeks, and then increase to 25 mg twice daily. 2) Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take the medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This drug should not be administered to certain patients. For example, those allergic to this drug or its components, patients with cardiac shock, those with heart conduction issues, patients with cor pulmonale, patients with metabolic disorders due to diabetes, patients with severely reduced myocardial function, patients with respiratory diseases such as asthma or chronic obstructive pulmonary disease, and pregnant or nursing women should not use this medication. Additionally, special caution should be exercised among diabetic patients or those with unstable cardiac function, severely impaired kidney or liver function, and elderly patients when using this medicine. This drug can lower blood pressure or reduce heart rate, so these patients should take it cautiously under medical supervision. While taking this medication, symptoms such as dizziness, headache, and fatigue may occur, and in severe cases, heart rate may slow too much or heart failure symptoms may worsen. Moreover, it can affect liver or kidney function, so regular testing is necessary. Do not suddenly stop taking this drug, especially for patients with cardiac conditions, as the dosage should be gradually reduced according to the physician's instructions. Abrupt discontinuation may exacerbate cardiac problems. This drug may interact with other medications, so if used with blood pressure medications, diabetes medications, antidepressants, anesthetics, etc., it is essential to inform the doctor or pharmacist. Additionally, caution is necessary if taken with alcohol or grapefruit juice, as it may affect the drug's efficacy. Pregnant or nursing women should not take this drug, and it is advisable not to use it in children or adolescents under 18 years of age since safety and efficacy have not been established. In case of an overdose, severe symptoms such as hypotension, cardiac function decline, and respiratory distress may occur, and immediate medical attention is required. This drug is difficult to remove via hemodialysis, so specialized treatment is needed. This drug may discolor when exposed to light, so it should be stored in a light-blocking container and kept out of reach of children. Transferring it to another container is not recommended as it may adversely affect quality.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disturbances
• nightmares
• psychosis

This drug must be stored in a special container that blocks light and air, with a storage temperature maintained between 1 to 30 degrees Celsius. Storing it this way will help maintain the drug's efficacy and safety.

Appearance

Reddish-brown round tablet

Package unit

90 tablets/box [(10 tablets/PTP×9)]