Levotidine Tablet (Levocetirizine Hydrochloride)

Adult dose

Adults: Administer 1 tablet (Levocetirizine Hydrochloride 5mg) orally once a day regardless of meals. Adjust as appropriate according to age and symptoms. For patients with renal impairment, adjust the dosage according to creatinine clearance (CLCR). - Mild (50 ≤ CLCR < 80): 1 tablet once a day - Moderate (30 ≤ CLCR < 50): 1 tablet twice a week - Severe (10 ≤ CLCR < 30): 1 tablet every three days

Child dose

Children aged 6 years and older: Administer 1 tablet (Levocetirizine Hydrochloride 5mg) orally once a day regardless of meals. Adjust as appropriate according to age and symptoms.

This medication should not be used by those who are allergic to certain components or have had hypersensitivity to hydroxizine or piperazine derivatives in the past. It should also not be administered to patients with severely impaired kidney function or those undergoing hemodialysis. It is safer for pregnant women or those who may become pregnant, as well as breastfeeding women, to avoid taking this medication. It must not be given to infants under 1 year of age, and children under 6 years should be given a liquid formulation instead of tablets. Patients with kidney or liver problems, as well as elderly individuals, should use this medication cautiously as the body concentration may increase. Taking this medication may lead to side effects such as drowsiness, fatigue, headache, and dizziness. In the gastrointestinal system, dry mouth, nausea, abdominal pain, and diarrhea may occur, so caution is advised. Rarely, cardiovascular abnormalities such as irregular heartbeats or increased blood pressure may occur. There have been reports of blood-related problems, allergic reactions, skin rashes, and visual disturbances. Liver and kidney function test values may change, so routine check-ups may be necessary. Drowsiness or lethargy may occur after taking this medication, so caution is needed when driving or operating machinery that requires concentration. Additionally, caution should be exercised to avoid increased drowsiness when taken in conjunction with alcohol or centrally acting depressants. This medication may increase the risk of urinary elimination disorders, so patients with urinary elimination problems such as spinal injuries or benign prostatic hyperplasia should be especially cautious. Taking this medication with alcohol may exacerbate side effects; therefore, it should not be combined. Interactions with other medications are relatively low, but it may affect certain drugs, so consultation with an expert is necessary if taking any other medications. Pregnant or breastfeeding women are safer not to take this medication, particularly since the drug components may be transmitted to babies through breast milk. In children, dosage adjustments are necessary for those under 12 years of age, and it must not be used in infants under 1 year of age. Elderly individuals are likely to have reduced kidney function, which may increase the drug's concentration, so it is important to start with a low dosage and monitor the condition closely. It is necessary to stop taking this medication before allergy testing to ensure accurate results. If overdosed, adults may experience severe drowsiness, while children may show restlessness and agitation. There is no specific antidote, so treatment should be symptomatic, and gastric lavage may be performed if necessary. This medication is not easily removed by hemodialysis, so immediate contact with a medical institution is recommended in case of overdose.

Serious side effects

• Urticaria
• angioedema
• anaphylactic shock
• edema
• increased blood pressure
• respiratory distress
• urticaria

Mild side effects

• Drowsiness
• lethargy
• headache
• numbness
• sleepiness
• fatigue
• dizziness
• heaviness in the head
• excitement
• thirst

This medication is sensitive to light, so it should be stored in a container that is not exposed to light. Moreover, it is best to store the medication at room temperature between 1 to 30 degrees Celsius, rather than in extremely hot or cold places.

Appearance

White or light yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle