Pantoprazole 20 mg (Pantoprazole Sodium Sesquihydrate)

Adult dosage

1. Treatment of mild reflux esophageal disease and related symptoms: Administer 20 mg of pantoprazole once daily orally before breakfast. Symptom relief generally occurs within 2 ∼ 4 weeks, and healing may usually be achieved with 4 weeks of treatment. If healing does not occur, an additional 4 weeks of treatment may achieve healing. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis: Administer 20 mg of pantoprazole once daily before breakfast. If recurrence occurs, increase the dose to 40 mg of pantoprazole daily, then reduce it back to 20 mg daily after healing. 3. Prevention of gastroduodenal ulcers caused by nonsteroidal anti-inflammatory drugs in patients requiring continuous treatment with nonsteroidal anti-inflammatory drugs: Administer 20mg of pantoprazole once daily. • No dose adjustment is necessary in elderly patients or patients with renal impairment. • Patients with hepatic impairment Do not exceed 20 mg of this medicine once daily in patients with severe hepatic impairment.

This medication should not be administered to patients with hypersensitivity to certain ingredients or benzimidazoles, as serious allergic reactions such as anaphylaxis, angioedema, and bronchospasm may occur. Additionally, this medication should not be used in patients taking certain antiviral agents such as atazanavir or nelfinavir, as the drug's effectiveness may be reduced when used together. It is also advisable that women who are in the first three months of pregnancy or who may become pregnant, as well as breastfeeding women, do not use this medication, as it may pose a risk to the fetus or newborn. Due to the inhibitory action on gastric acid secretion, long-term use of this medication may lead to vitamin B12 absorption disorders. Therefore, regular check-ups are required if taken long-term. Moreover, elderly patients over 65 or those with a history of gastric ulcers, duodenal ulcers, or gastrointestinal bleeding should be cautious, as the risk of gastrointestinal bleeding may increase with this medication. Prolonged high-dose use may increase the risk of fractures; hence, it is recommended to use the minimum dosage for the shortest duration possible. While taking this medication, hypomagnesemia may occasionally occur, which can lead to hypocalcemia or hypokalemia. It is important to monitor magnesium levels regularly, especially during long-term treatment of more than a year. This medication may slightly increase the risk of bacterial infections in the gastrointestinal tract due to the suppression of gastric acid secretion. If diarrhea persists, consult a physician. Dizziness or visual disturbances may occur; therefore, caution is needed while driving or operating machinery. Additionally, since this medication is metabolized in the liver, patients with severe liver impairment may need to adjust the dosage and undergo regular liver enzyme checks. This medication should not be used in combination with certain drugs such as atazanavir, nelfinavir, or rilpivirine due to potential interactions. Consult a physician regarding the usage of this medication if pregnant or breastfeeding, as it may pose risks to the fetus or newborn. There is insufficient experience using this medication in children under 12 years of age, and it is not recommended. Specific symptoms of overdose are not known, but if any abnormalities occur, seek medical attention immediately. It is advisable to swallow the tablet whole without chewing or crushing it. In case of long-term use, follow the physician's instructions regarding minimal dosage and appropriate duration, and monitor the treatment progress carefully. This medication should be stored out of reach of children and should not be transferred to other containers.

• Anaphylaxis
• anaphylactic shock
• angioedema
• bronchospasm
• acute interstitial nephritis
• urticaria
• upper abdominal pain
• constipation
• bloating
• diarrhea

This medication is sensitive to light, so it should be stored in a light-protected container. It is also important to maintain a room temperature of between 1 to 30 degrees Celsius when storing it. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

Yellow enteric-coated oval tablet

Package unit

30 tablets/bottle