Lobaga 20 mg (Rosuvastatin Calcium)

Adult dosage

Patients with primary hypercholesterolemia, mixed dyslipidemia, dysbetalipoproteinemia, and homozygous familial hypercholesterolemia can take the medication at any time of the day regardless of meals. The starting dose is 5 mg once daily. If greater reductions in LDL cholesterol are required, the maintenance dose can be adjusted to 10 mg once daily, with LDL cholesterol levels and patient response assessed at intervals of 4 weeks or more.

This medication should not be used by individuals who are allergic to any of its components. Patients with active liver disease or abnormally high liver enzyme levels should also avoid this medication. Women who are pregnant or nursing should not use this drug. Patients at high risk for muscle disorders, particularly those on high doses, should exercise caution as there are several risk factors involved. Patients with lactose intolerance or specific genetic metabolic disorders should not take this medication. This drug may affect liver function, so those with a history of liver disease or high alcohol consumption should use caution. Muscle-related side effects such as myalgia, myopathy, and rarely, rhabdomyolysis can occur, and any symptoms should be reported to healthcare professionals immediately. Muscle enzyme levels should be tested before and during treatment, and if abnormalities are noted, dosing should be adjusted or discontinued. In cases of acute severe conditions or serious physical illnesses, use should be discontinued. Rarely, this drug can cause severe skin reactions or liver damage, so if symptoms such as skin rash or jaundice appear, treatment should be stopped immediately. There may be interactions with other medications, so it is crucial to inform healthcare providers about any other medications being taken. Particularly, caution is warranted when co-administering drugs that may increase the risk of muscle toxicity. Pregnant or nursing women should not use this medication, and women of childbearing potential should use appropriate contraception. In case of overdose, no specific antidote exists, hence treatment should be symptomatic with monitoring of liver function and muscle enzymes. Caution is advisable when driving or operating machinery as dizziness may occur.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), chest tightness, difficulty breathing, jaundice, hepatitis, severe myopathy, ophthalmoplegia, acute renal failure, oliguria, thrombocytopenia, liver failure, rhabdomyolysis, immune-mediated necrotizing myopathy, severe headaches, seizures, altered consciousness, visual disturbances, paralysis, edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• diarrhea
• fatigue

This medication should be stored in a tightly closed container to protect it from air and moisture. The storage temperature should be maintained between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablets

Package unit

PE bottle packaging - 30 tablets/bottle, PE bottle packaging - 100 tablets/bottle