Clamoxen Duo Syrup (Amoxicillin-Potassium Clavulanate (7:1))

Adult dose

For mild to moderate infections such as recurrent tonsillitis, take 25 mg/3.6 mg per weight kg divided into 2 doses daily. For severe infections such as otitis media and sinusitis, take 45 mg/6.4 mg per weight kg divided into 2 doses daily. To minimize potential gastrointestinal intolerance, take the medication early in the meal. The absorption of amoxicillin-clavulanate is optimized when taken early in the meal.

Child dose

The 7:1 syrup is not suitable for children under 2 months and also not suitable for pediatric patients with renal failure.

This medication contains the artificial sweetener aspartame, which is metabolized in the body to phenylalanine. Therefore, it should not be administered to patients with phenylketonuria, a genetic disorder. Patients who have had allergic reactions to this medication or beta-lactam antibiotics should not use this medication. In particular, patients with infectious mononucleosis or lymphocytic leukemia are at increased risk of rash and should be cautious. Patients with liver or kidney function issues should use this medication carefully, and those with allergic tendencies or gastrointestinal symptoms should consult a doctor before use. This medication can cause various side effects in the digestive system, such as diarrhea, abdominal pain, nausea, and vomiting. Severe colitis, such as membranous colitis, can occur, so if abdominal pain or frequent diarrhea occurs, use should be stopped immediately and a hospital visit is necessary. Liver function abnormalities may also occur, particularly in the elderly or with prolonged use. Skin rashes or itching may occur, and in severe cases, serious skin reactions like Stevens-Johnson syndrome may appear, necessitating immediate discontinuation. Blood-related adverse reactions such as leukopenia, thrombocytopenia, and anemia have been reported rarely, and bleeding tendencies may be present, so consult a doctor if bleeding symptoms occur. This medication is excreted via the kidneys and liver, so dose adjustment is necessary in cases of kidney or liver disease, and regular monitoring of kidney function, liver function, and blood condition is required during long-term use. Pregnant or breastfeeding women should consult a doctor before using this medication and should avoid use, particularly during the first three months of pregnancy. Safety in children, especially in newborns under 2 months or premature infants, has not been established, so caution is needed. In the elderly, adverse reactions may appear more readily due to decreased body function, and there is a risk of bleeding due to vitamin K deficiency, so dosing and intervals should be adjusted and used cautiously. This medication may interact with other drugs, so it is essential to inform healthcare providers of current medications, especially when used with anticoagulants or other antibiotics. In cases of overdose, gastrointestinal symptoms, rashes, drowsiness, convulsions may appear, so use should be stopped immediately, and emergency care should be sought. The medication should be shaken well before use, and after preparation, it should be stored in the refrigerator and used within 7 days. Finally, it is important to take this medication for the exact period necessary to prevent the emergence of resistant bacteria. If any unusual symptoms occur during use, consult a doctor immediately.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, pain in mouth/eye mucosa, severe skin adverse reactions, asthma attacks, respiratory problems accompanied by cough and fever, respiratory issues, yellowing of the skin or eyes (jaundice), extreme lethargy, liver issues (jaundice), sudden and severe headaches, thunderclap headaches

Mild side effects

Diarrhea, membranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, gastric acidity, xerostomia, candidiasis, hematochezia, itching, erythema multiforme, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), angioedema, thrombocytopenic purpura, anemia, eosinophilia, leukemia, agranulocytosis, mucosal candidiasis, vaginal itching, drowsiness, insomnia, dizziness, headache, taste disturbance, malaise, dermatitis

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to store it in a cool, dry place below 25 degrees Celsius to maintain its effectiveness.

Appearance

A syrup preparation in the form of a whitish powder with a distinctive scent, to be dissolved before use.

Package unit

50 mL/bottle, 500 mL/bottle