Rosuvastatin Calcium 5 mg Tablets

Adult dosage

Administer once daily at any time of the day, with or without food. The initial dose is 5 milligrams once daily, and if greater LDL cholesterol reduction is needed, the maintenance dose can be adjusted accordingly. The maintenance dose is typically 10 milligrams once daily, where most patients are regulated at this dose. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response, typically at intervals of 4 weeks or longer.

This drug should not be administered to certain patients. First, it should not be taken by individuals who are allergic to any component of this medication. It should also not be used in cases of active liver disease or when liver enzyme levels are abnormally high. Patients with muscle disorders or severe renal impairment should avoid this medication. Women who are pregnant or breastfeeding, as well as women of childbearing potential without appropriate contraception, should not take this drug. Additionally, high doses are especially prohibited for patients at risk of myopathy or rhabdomyolysis. This drug contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. Patients taking this medication should have their liver function and muscle condition monitored regularly. Particular caution is needed for patients who consume significant amounts of alcohol or have a history of liver disease. If muscle pain or weakness symptoms arise, notify healthcare providers immediately, and in severe cases, discontinue the medication. In acute illness or severe conditions, it is advisable to stop taking this medication. Moreover, this drug can interact with other medications, so be sure to inform the prescribing physician of any other medications being taken. In particular, using it alongside fibric acid derivatives may increase the risk of muscle-related side effects. Pregnant or breastfeeding women should not use this drug, and women of childbearing potential must ensure contraception. In case of overdose, there are no specific antidotes, so treatment should be symptomatic and include liver and muscle testing. This drug is known not to significantly affect driving or machine operation; however, be cautious of symptoms such as dizziness. Finally, this drug may show higher blood concentration levels in Asians, so dosage adjustments may be necessary.

Serious side effects

Allergic reactions including hives and angioedema, severe swelling (edema), chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe skin reactions, severe muscle weakness, ocular myasthenia, rhabdomyolysis, immune-mediated necrotizing myopathy, acute renal failure, oliguria, thrombocytopenia, elevated serum creatinine.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• fatigue
• diarrhea

Store this drug in a tightly closed container to protect it from air and moisture. It is recommended to keep the storage temperature between 1 to 30 degrees Celsius in a cool area.

Appearance

Yellow round film-coated tablets

Package unit

28 tablets (14 tablets/PTP x 2)