Clobust Tablet (Clopidogrel Sulfate)

Adult dose

1. For patients with ischemic stroke, myocardial infarction, or peripheral artery disease, administer Clopidogrel 75 mg orally once daily. 2. For patients with acute coronary syndrome (unstable angina or non-ST elevation myocardial infarction), start with a loading dose of 300 mg orally once daily on the day of treatment initiation, followed by a maintenance dose of 75 mg orally once daily. At this time, administer aspirin 75 - 325 mg once daily concurrently with this medication.

This medication is a drug that prevents platelets from aggregating, thereby preventing blood clotting. Individuals with a genetic deficiency in specific enzymes (CYP2C19) may experience reduced efficacy of this medication, and such individuals should consult their physician to consider alternative treatment options. Taking this medication with drugs that activate these enzymes may increase the risk of bleeding, so it is advisable not to take them together. Patients who are allergic to this medication or its components or those with bleeding, severely impaired liver function, women who are breastfeeding, and those with genetic conditions such as lactose intolerance should not take this medication. Patients at high risk of bleeding or those with coagulation disorders and patients scheduled for surgery should take this medication with caution, and it may be necessary to discontinue the medication for a certain period before surgery. If symptoms of bleeding or abnormalities in blood appear during treatment, it is crucial to inform medical personnel immediately. The risk of bleeding may increase when this medication is taken with other drugs that also pose a bleeding risk, so caution is necessary during concurrent use. Pregnant women should not delay treatment for serious cardiovascular diseases, though the effects on the fetus are unclear, and it is advisable to discontinue administration for a certain period before delivery due to bleeding risks. Breastfeeding women should consult their physician regarding the impact of this medication potentially entering breast milk and affecting the infant. The safety and efficacy in children have not yet been established. Elderly patients are at an increased risk of bleeding due to decreased bodily functions, so caution is warranted, and their condition should be monitored closely. In the case of overdose, the risk of bleeding may increase, so it is important to adhere to the prescribed dosage, and any unusual symptoms should be discussed with a healthcare professional immediately. This medication should be kept out of the reach of children, and it is advisable to avoid transferring it to other containers, as it may affect the quality of the drug.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, mouth/eye mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and very severe headache, thunderclap headache, seizures, confusion, vision disturbances, paralysis, urination

Mild side effects

• Chest pain
• accidental injury
• influenza-like illness
• pain
• fatigue
• edema
• hypertension
• headache
• dizziness
• abdominal pain

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1°C and 30°C to preserve its effectiveness.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle