Clarithromycin Tablet 500mg (Clarithromycin)

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medication twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Helicobacter pylori eradication in patients with duodenal ulcers: Administer 500mg (potency) of this medication three times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup

This drug should not be used by patients who are allergic to specific ingredients. Patients with severe heart rhythm disturbances or significantly impaired liver or kidney function should use caution. Pregnant or nursing women are advised not to take this medication. Serious side effects may occur when taken with certain other medications, so it is essential to consult a physician. If allergic reactions or serious abnormal symptoms occur during treatment, discontinue use immediately and visit a hospital. Various side effects such as gastrointestinal discomfort, skin rashes, and neurological abnormalities have been reported, so vigilance is required in case of symptoms. Prolonged or high-dose use may lead to auditory abnormalities or muscle-related side effects, so care should be taken. Elderly patients or those with impaired kidney function may require dosage adjustments. When taking this medication, it is crucial to adhere strictly to the prescribed duration and dosage to prevent bacterial resistance. Interactions with other medications may change the drug's efficacy, so it is important to inform about any concurrent medication. Overdose may result in gastrointestinal disturbances or central nervous system abnormalities, and immediate emergency treatment is needed in such cases.

Shock, anaphylactic symptoms, difficulty breathing, convulsions, redness, rash, itching, hives, skin redness, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disorder, decreased appetite, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, kidney failure, rhabdomyolysis, stomatitis, oral mucositis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, auditory impairment, hypoglycemia, tinnitus, hearing loss, vomiting, purpuric rash, acute generalized exanthematous pustulosis, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactic reaction, angioedema, decreased appetite, insomnia, irritability, noise intolerance, psychotic disorder, confusion state, abnormal dreams, muscle cramps, musculoskeletal rigidity, myopathy, vasodilation, cardiac arrest, atrial fibrillation, premature contraction, palpitations, asthma, nasal bleeding, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, cholestasis, elevated alanine aminotransferase, elevated aspartate aminotransferase, hepatitis, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, myalgia, kidney failure, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication is sensitive to light and must be stored in a special container that prevents light exposure. Additionally, it is important to store it at room temperature between 15 degrees and 30 degrees to maintain its effectiveness.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle