Medication info
Dilaten Tablet 25 mg (Carvedilol)

Dilaten Tablet 25 mg (Carvedilol)

Prescription medicationTabletOral
Ingredient · strength
Carvedilol›25mg / 1 tablet
Manufacturer / importer
Daehan New Pharm Co., Ltd.
Appearance
White round tablet
Packaging
90 tablets (10 tablets/PTP X 9)
Approval status
Active

MFDS item code 201905923 · Approved 2019.08.21

Summary

Main use
Treatment of essential hypertension and chronic stable angina; adjunctive treatment of congestive heart failure
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first two days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients For some elderly patients, a dose of 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first two days, take 12.5 mg of this medicine twice daily by mouth, then take 25 mg twice daily by mouth. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure 1) In general, the initial treatment is 3.125 mg of this medicine twice daily by mouth for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase it to 12.5 mg twice daily for 2 weeks, and then increase it to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the maximum dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To regulate the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Ingredients

Manufacturer
Daehan New Pharm Co., Ltd.

Efficacy & effects

Treatment of essential hypertension and chronic stable angina; adjunctive treatment of congestive heart failure

  • Essential hypertension
  • chronic stable angina
  • congestive heart failure
View approved original text

This medication is used to treat cardiovascular diseases such as essential hypertension, chronic stable angina, and congestive heart failure. It is particularly effective as an adjunctive treatment when combined with diuretics, digoxin, ACE inhibitors, and other vasodilators. It helps in controlling the patient's blood pressure and improving heart function, thereby alleviating symptoms and enhancing quality of life. This medication is actively utilized in the management of such cardiovascular diseases.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first two days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients For some elderly patients, a dose of 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first two days, take 12.5 mg of this medicine twice daily by mouth, then take 25 mg twice daily by mouth. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure 1) In general, the initial treatment is 3.125 mg of this medicine twice daily by mouth for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase it to 12.5 mg twice daily for 2 weeks, and then increase it to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the maximum dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To regulate the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Precautions

This medication should not be used in certain patients. For example, patients with allergies to this medication or its components, those in cardiogenic shock, patients with conduction problems in the heart, patients with cor pulmonale, those with diabetic ketoacidosis, patients with severely impaired cardiac function, asthma or chronic obstructive pulmonary disease patients, those with secondary hypertension, patients with certain cardiac conditions, and pregnant or nursing women should not be administered this medication. Moreover, diabetic patients or those with a history of hypersensitivity, patients with low blood pressure, patients with impaired kidney or liver function, elderly patients, and those taking specific medications should exercise special caution when using this medication. Since this medication affects the heart and blood pressure, patients with heart disease or unstable blood pressure should take it cautiously under a physician's guidance. During treatment, symptoms such as dizziness, fatigue, and headache may occur, and in severe cases, there may be bradycardia or a sudden drop in blood pressure. Rarely, mental disturbances, skin rashes, liver dysfunction, and respiratory problems may occur, so immediate consultation with medical personnel is required if any unusual symptoms arise. With long-term use, regular monitoring of heart function, blood pressure, liver, and kidney functions is required. Abrupt discontinuation may worsen cardiac symptoms, so the dosage should be gradually reduced as per medical advice. Particular attention should be given to blood sugar control in elderly or diabetic patients. This medication can interact with other drugs, so it is essential to inform the doctor or pharmacist if you are taking any other medications. Also, it should not be used during pregnancy or lactation, and safety has not been established in children and adolescents under 18 years, hence it is not recommended. In case of overdose, serious cardiac and respiratory issues may occur, so it is crucial to adhere to dosage guidelines and promptly report any unusual symptoms to healthcare professionals. This medication is sensitive to light, so it should be stored in a container that protects it from light and kept in a safe place out of reach of children.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucination
  • confusion
  • depression
  • sleep disorders
  • nightmares
  • psychosis
Show 61 more
  • severe bradycardia
  • shock
  • complete atrioventricular block
  • heart failure
  • cardiac arrest
  • significant decrease in blood pressure
  • loss of consciousness
  • decreased pulse rate
  • limb coldness
  • edema
  • exacerbation of heart failure
  • asystole
  • worsening of renal function
  • renal failure
  • increased respiratory tract resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichen planus-like reaction
  • sweating
  • allergic rash
  • changes in serum aminotransferases
  • thrombocytopenia
  • leukopenia
  • hypoglycemia
  • masking of hyperthyroid function
  • hyperglycemia
  • weight gain
  • increased blood cholesterol
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension in angina patients
  • liver dysfunction
  • jaundice
  • limb pain
  • decreased tear production
  • sensory impairment
  • visual disturbances
  • eye irritation
  • dry mouth
  • urinary disorders
  • sexual dysfunction
  • allergic reactions
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • marked decrease in blood pressure
  • slowed heart rate
  • myocardial weakness
  • cardiogenic shock
  • asystole
  • cardiac arrest
  • difficulty breathing
  • bronchospasm
  • vomiting
  • altered consciousness
  • generalized seizures

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a special container that does not allow light to penetrate. Additionally, it is advised to store the medication at room temperature, which should not be too low or too high, preferably between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White round tablet

Package unit

90 tablets (10 tablets/PTP X 9)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.