Medication info
Clarithon Tablet (Clarithromycin)

Clarithon Tablet (Clarithromycin)

Prescription medicationTablet
Ingredient · strength
Clarithromycin›250mg
Manufacturer / importer
Independent Bio Pharmaceutical Co., Ltd.
Appearance
Yellow oval film-coated tablet
Packaging
Domestic use - 30 tablets/bottle, Domestic use - 100 tablets/bottle
Approval status
Active

MFDS item code 201905908 · Approved 2019.08.21 · Insurance code 057700320

Summary

Main use
Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter pylori infection in duodenal ulcers
Who uses it
Adults · Children
Adult dosage
○ Adults : The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7~14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily; for severe infections, administer 250mg (potency) twice daily. Do not administer this drug to these patients for more than 14 days. ○ Mycobacterial infections : Administer 500mg (potency) of this drug twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers : Administer 500mg (potency) of this drug three times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1~14), and administer omeprazole 40mg once daily for 28 days (days 1~28).
Children's dosage
Children aged 12 years and older: same as adults Children under 12 years: use clarithromycin dry syrup.

Ingredients

Manufacturer
Independent Bio Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter pylori infection in duodenal ulcers

  • Bronchitis
  • pneumonia
  • pharyngitis
  • sinusitis
  • skin and soft tissue infections
  • mycobacterial infections
  • duodenal ulcers.
View approved original text

This medication works effectively against various bacteria and microorganisms. It is used to treat lower respiratory tract infections such as bronchitis and pneumonia, as well as upper respiratory tract infections like pharyngitis and sinusitis. It is also effective for skin and soft tissue infections, and helps to treat mycobacterial infections caused by Mycobacterium avium and intracellular infections. In patients with duodenal ulcers, it is used to eradicate Helicobacter pylori. This drug improves infections against various pathogens including various strains of pneumococcus, influenza bacteria, and chlamydia.

Dosage and Administration

Adult dosage

○ Adults : The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7~14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily; for severe infections, administer 250mg (potency) twice daily. Do not administer this drug to these patients for more than 14 days. ○ Mycobacterial infections : Administer 500mg (potency) of this drug twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers : Administer 500mg (potency) of this drug three times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1~14), and administer omeprazole 40mg once daily for 28 days (days 1~28).

Children's dosage

Children aged 12 years and older: same as adults Children under 12 years: use clarithromycin dry syrup.

Precautions

This medication should not be used in patients who are allergic to certain components. Particularly, patients who have had an allergic reaction to similar antibiotics should be cautious. Patients with severe heart disease or impaired liver and kidney function should use this drug with caution. It is safer for pregnant or breastfeeding women not to take this medication. Since interactions may occur when taken with other medications, patients should inform their healthcare provider of any other medications they are taking. This drug can rarely cause serious allergic reactions, skin rashes, liver dysfunction, gastrointestinal disorders, etc., so patients should consult healthcare professionals immediately if any abnormal symptoms occur. Prolonged or high-dose usage may lead to auditory disturbances or muscle-related side effects, so caution is needed. It is crucial to take this medication only for the necessary duration to prevent the development of antibiotic resistance, and it should be taken consistently for the prescribed duration even if symptoms improve. There may be symptoms such as dizziness or confusion while driving or operating machinery, so caution is warranted. Overdose may lead to gastrointestinal symptoms or nervous system abnormalities, so the dosage must be adhered to, and any abnormal symptoms should be reported to healthcare professionals immediately.

Side effects

  • Shock
  • anaphylactic symptoms
  • dyspnea
  • convulsions
  • flushing
  • rash
  • itching
  • urticaria
  • skin erythema
  • angioedema
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  • joint swelling
  • drug eruption
  • abdominal distention
  • nausea
  • vomiting
  • dyspepsia
  • abdominal pain
  • malaise
  • flatulence
  • diarrhea
  • oral mucosal erosion
  • upper abdominal pain
  • thirst
  • tooth discoloration
  • pancreatitis
  • increased amylase
  • dysgeusia
  • anorexia
  • constipation
  • discoloration of stool
  • pseudomembranous colitis
  • hemorrhagic colitis
  • fever
  • cough
  • abnormal chest X-ray
  • eosinophilia
  • eosinophilic lung infiltrate
  • interstitial pneumonia
  • chronic bronchitis
  • acute maxillary sinusitis
  • thrombocytopenia
  • pancytopenia
  • hemolytic anemia
  • leukopenia
  • agranulocytosis
  • dizziness
  • depression
  • loss of taste
  • loss of smell
  • anxiety
  • insomnia
  • nightmares
  • tinnitus
  • confusion
  • disorientation
  • hallucinations
  • psychosis
  • depersonalization
  • convulsions
  • tremors
  • paresthesia
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • allergic purpura
  • drug rash
  • jaundice
  • hepatocellular hepatitis
  • cholestatic hepatitis
  • increased liver enzyme levels
  • liver dysfunction
  • hepatic failure
  • fulminant hepatitis
  • elevated AST
  • elevated ALT
  • elevated γ-GTP
  • elevated LDH
  • elevated ALP
  • increased total bilirubin
  • elevated serum creatinine
  • elevated BUN
  • interstitial nephritis
  • renal failure
  • rhabdomyolysis
  • stomatitis
  • oral mucositis
  • oral candidiasis
  • QT prolongation
  • ventricular tachycardia
  • malaise
  • headache
  • taste distortion
  • hearing loss
  • paresthesia
  • arthralgia
  • myalgia
  • olfactory disorder
  • hypoglycemia
  • tinnitus
  • hearing impairment
  • muscle cramps
  • musculoskeletal stiffness
  • myopathy
  • elevated serum creatinine
  • elevated blood urea nitrogen
  • nephritis
  • phlebitis at the injection site
  • injection site pain
  • inflammation at the injection site
  • fever
  • asthenia
  • chest pain
  • chills
  • fatigue
  • abnormal albumin globulin ratio
  • elevated serum alkaline phosphatase
  • elevated blood lactate dehydrogenase
  • increased International Normalized Ratio
  • prolonged prothrombin time
  • urine discoloration

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to keep the storage temperature between 1 and 30 degrees Celsius. Storing it this way can help maintain the drug's efficacy and safety for a longer duration.

Appearance and packaging

Appearance

Yellow oval film-coated tablet

Package unit

Domestic use - 30 tablets/bottle, Domestic use - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.