Medication info
DICABEM 25 mg Tablets (Carvedilol)

DICABEM 25 mg Tablets (Carvedilol)

Prescription medicationTabletOral
Ingredient · strength
Carvedilol›25mg / 1 tablet
Manufacturer / importer
Mothers Pharma Co., Ltd.
Appearance
White, round tablet
Packaging
90 tablets/box [(10 tablets/PTP) x 9]
Approval status
Active

MFDS item code 201905686 · Approved 2019.08.13 · Insurance code 622803940

Summary

Main use
Treatment of essential hypertension and chronic stable angina
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without a doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If an increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults For some older adults, 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily.

Ingredients

Manufacturer
Mothers Pharma Co., Ltd.

Efficacy & effects

Treatment of essential hypertension and chronic stable angina

  • Essential hypertension
  • chronic stable angina
View approved original text

This medication is used for essential hypertension and chronic stable angina.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without a doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If an increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults For some older adults, 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily.

Precautions

This medication should not be used in patients with certain heart diseases or respiratory diseases. It is essential not to administer it to patients with very slow heart rates or problems with heart conduction, and to those with very weak heart function. Caution should be exercised in patients with lung diseases or asthma, and in those with metabolic disorders due to diabetes, as it may worsen their symptoms. It is safe to avoid this medication in pregnant or breastfeeding women. During the use of this drug, regular monitoring of blood pressure and heart rate is necessary, and consistent cardiac function testing is required. Sudden discontinuation of the drug may worsen symptoms of heart disease, so the dosage should be reduced gradually according to a doctor's instructions. This medication may interact with other drugs, so it is crucial to inform healthcare providers of any other medications being taken. Special care is needed when taken in combination with antihypertensives, diabetes medications, antidepressants, and sedatives, as side effects may increase. Dizziness, fatigue, headache, and other symptoms may occur, and if heart rate slows excessively or blood pressure drops too low, consult a healthcare provider immediately. In case of overdose, there is a risk of severe hypotension, heart function decline, and breathing difficulties, so the prescribed dosage must be adhered to. This medication has not been established for safety and efficacy in children and adolescents, so it is advisable to avoid using it in these populations. In elderly patients, drug concentration may increase due to decreased liver function, so treatment should start at a low dose and be monitored closely.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucination
  • confusion
  • depression
  • sleep disorders
  • nightmares
  • psychosis
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  • severe bradycardia
  • shock
  • complete atrioventricular block
  • heart failure
  • cardiac arrest
  • significantly low blood pressure
  • loss of consciousness
  • decreased heart rate
  • cold extremities
  • edema
  • worsening heart failure
  • asystole
  • worsening kidney function
  • renal failure
  • increased airway resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichenoid reaction
  • excessive sweating
  • allergic rash
  • serum aminotransferase changes
  • thrombocytopenia
  • leukopenia
  • latent diabetes mellitus onset
  • hypoglycemia
  • concealment of hyperthyroidism
  • hyperglycemia
  • weight gain
  • increased blood cholesterol
  • bradycardia
  • hypotension
  • breathlessness
  • hypertension in angina
  • liver dysfunction
  • jaundice
  • limb pain
  • reduced tears
  • sensory disturbances
  • visual impairment
  • eye irritation
  • dry mouth
  • urinary disorders
  • sexual dysfunction
  • allergic reactions
  • cerebrovascular disorders
  • increased bronchial secretions
  • tachycardia
  • hyperglycemia
  • flushing
  • leukocytosis
  • hematuria
  • myocardial infarction
  • hyperkalemia
  • blood pressure reduction
  • drowsiness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that protects it from light, at room temperature between 1 to 30 degrees Celsius. Storing it this way can maintain the drug's efficacy and safety.

Appearance and packaging

Appearance

White, round tablet

Package unit

90 tablets/box [(10 tablets/PTP) x 9]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.