DICABAM Tablet 12.5mg (Carvedilol)

Adult dose

Do not increase the dose or discontinue treatment without a doctor's instructions. 1. Essential hypertension 1) Adults (1) Administer carvedilol 12.5 mg orally once daily for the first 2 days, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) Administer 12.5 mg of this drug twice daily for the first 2 days, then administer 25 mg twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding older adults), it may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this drug, the standard treatment regimen already being used (the conventional treatment regimen for chronic heart failure, generally including an ACE inhibitor, a diuretic, and a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this drug. 1) The usual initial dose is 3.125 mg of this drug twice daily for 2 weeks. If the patient tolerates this treatment well, increase to 6.25 mg twice daily for 2 weeks, then increase to 12.5 mg twice daily for 2 weeks, and then increase to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the highest dose the patient can tolerate. 3) The effective minimum dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily in patients weighing 85 kg or less, and 50 mg twice daily in patients weighing more than 85 kg. 4) To control the rate of absorption, administration with meals in the morning and evening is recommended. Taking this drug with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication is often contraindicated in specific patients. For example, individuals allergic to this medication or its components, those with severely impaired cardiac function, those with bradycardia, those with pulmonary-related cardiac diseases, those with severe metabolic disorders due to diabetes, and those with respiratory diseases such as asthma or chronic obstructive pulmonary disease may be at risk when taking this medication. Additionally, pregnant or breastfeeding women and those with severely impaired liver or kidney function should avoid this medication. When using this medication, special caution should be exercised in patients with diabetes, those with severe allergic reactions, the elderly, those with low blood pressure, and those with heart disease. During treatment, symptoms such as dizziness, fatigue, and headaches may occur, and in rare cases, heart rate may slow down or blood pressure may drop too low. If cardiac function worsens or symptoms such as severe swelling or shortness of breath occur, medical consultation should be sought immediately. This medication can affect liver and kidney function; therefore, regular check-ups are required. Do not suddenly discontinue this medication, especially in patients with heart disease; the dosage should be reduced gradually. This medication may interact with other drugs, so it is essential to inform your doctor or pharmacist about any medications currently being taken. Moreover, caution is warranted when taking this medication with alcohol or grapefruit juice. This medication has not been established as safe or effective in children or adolescents and is not recommended. Elderly patients may experience increased drug concentration due to decreased liver function, and should start with lower doses due to the risk of excessive hypotension resulting in stroke. In cases of overdose, severe hypotension, arrhythmias, and shortness of breath may occur, and immediate medical attention is necessary for appropriate treatment. Finally, this medication may discolor when exposed to light, so it should be stored in a light-blocking container and kept out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disturbances
• nightmares
• psychosis

This medication may be sensitive to light, so it should be stored in a light-protective container. Additionally, it is best to store the medication at room temperatures between 1 degree and 30 degrees Celsius. This helps to maintain the medication's effectiveness and allows for safe usage.

Appearance

Reddish-brown round tablet

Package unit

90 tablets (10 tablets/PTP×9) - 90 tablets/PTP [90 tablets (10 tablets/PTP×9)]