Medication info
Carbacity Tablet 12.5mg (Carvedilol)

Carbacity Tablet 12.5mg (Carvedilol)

Prescription medicationTabletOral
Ingredient · strength
Carvedilol›12.5mg / 1 tablet
Manufacturer / importer
CTC Bio, Co., Ltd.
Appearance
Brownish-red round tablets
Packaging
90 tablets (10 tablets/PTP x 9)
Approval status
Active

MFDS item code 201905582 · Approved 2019.08.07 · Insurance code 669502500

Summary

Main use
Adjunctive treatment of congestive heart failure; treatment of essential hypertension and chronic stable angina
Who takes it
Adults
Adult dose
Do not increase the dose or discontinue this medication without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults Some older adults may achieve sufficient efficacy with 12.5 mg once daily. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this drug orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed, the dose may be increased to 50 mg twice daily (except in older adults). 3. Congestive heart failure Before starting treatment with this drug, the standard treatment regimen already being used (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this drug. 1) Generally, the initial dose is 3.125 mg of this drug orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the absorption rate, it is recommended that the drug be taken with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Ingredients

Manufacturer
CTC Bio, Co., Ltd.

Efficacy & effects

Adjunctive treatment of congestive heart failure; treatment of essential hypertension and chronic stable angina

  • Essential hypertension
  • chronic stable angina
  • congestive heart failure
View approved original text

This medication is used to treat essential hypertension, chronic stable angina, and congestive heart failure. It is especially used in combination with diuretics, digitalis preparations, ACE inhibitors, and other vasodilators as an adjunctive treatment, aiding in the effective management of cardiovascular health.

How to take

Adult dose

Do not increase the dose or discontinue this medication without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults Some older adults may achieve sufficient efficacy with 12.5 mg once daily. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this drug orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed, the dose may be increased to 50 mg twice daily (except in older adults). 3. Congestive heart failure Before starting treatment with this drug, the standard treatment regimen already being used (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this drug. 1) Generally, the initial dose is 3.125 mg of this drug orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the absorption rate, it is recommended that the drug be taken with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

Precautions

This medication is often contraindicated for certain patients. For instance, it should not be given to individuals with allergies to this drug or its components, those with severely impaired cardiac function, those with bradycardia, those with cardiac diseases related to pulmonary function, those with severe metabolic disorders due to diabetes, and those with respiratory diseases like asthma or chronic obstructive pulmonary disease. It is also advisable for pregnant or breastfeeding women not to use this medication. Caution is particularly needed for patients with diabetes, severe allergic reactions, heart disease, impaired kidney or liver function, and the elderly. This drug can affect heart rate and blood pressure, so careful monitoring according to the doctor's instructions is necessary for these patients. During treatment, symptoms such as dizziness, fatigue, and headache may occur, and in severe cases, serious side effects such as bradycardia, worsening heart failure, and hypotension can arise. If such symptoms occur, immediate consultation with a physician is required. This medication requires regular monitoring of heart function, blood pressure, and liver and kidney function during prolonged use, and abrupt discontinuation may worsen symptoms, so tapering off under a doctor's guidance is essential. This drug may interact with other medications, so if you are taking any other medications, it is crucial to inform your doctor or pharmacist. Special caution is needed when taking it along with antihypertensives, diabetes medications, antidepressants, antiarrhythmics, or anesthetics. Pregnant or breastfeeding women should not take this medication, and it has not established safety and efficacy for children or adolescents under 18, so its use should be avoided. For the elderly, the liver function may be reduced, resulting in increased levels of this medication, thus starting at a lower dose while closely monitoring the condition is recommended. In case of overdose, severe symptoms such as hypotension, bradycardia, impaired heart function, respiratory distress, and altered consciousness may occur, so immediate contact with a medical institution for appropriate treatment is necessary. This drug may discolor when exposed to light, so it should be stored in a container that blocks light and kept out of reach of children. Avoid transferring it to another container.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucinations
  • confusion
  • depression
  • sleep disorders
  • nightmares
  • psychosis
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  • severe bradycardia
  • shock
  • complete heart block
  • heart failure
  • cardiac arrest
  • significant hypotension
  • loss of consciousness
  • decreased pulse rate
  • cold extremities
  • edema
  • asystole
  • worsening renal function
  • renal failure
  • increased airway resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichenoid reactions
  • sweating
  • allergic rash
  • serum aminotransferase changes
  • thrombocytopenia
  • leukopenia
  • latent diabetes mellitus development
  • hypoglycemia
  • masking of hyperthyroidism
  • hyperglycemia
  • weight gain
  • increased blood cholesterol
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension in angina
  • liver dysfunction
  • jaundice
  • limb pain
  • decreased tear production
  • sensory disturbances
  • visual disturbances
  • eye irritation
  • dry mouth
  • urinary disorders
  • sexual dysfunction
  • allergic reactions
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • marked decrease in blood pressure
  • slowed heart rate
  • myocardial weakening
  • asystole
  • dyspnea
  • bronchospasm
  • vomiting
  • altered consciousness
  • generalized seizure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it is important to maintain a temperature between 1 degree and 30 degrees Celsius while storing the drug. Proper storage will help maintain the drug's effectiveness.

Appearance and packaging

Appearance

Brownish-red round tablets

Package unit

90 tablets (10 tablets/PTP x 9)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.