Qsymia Capsule 7.5mg/46mg

Adult dose

Take this medicine every morning, with or without food; avoid taking it in the evening because it may cause insomnia. 1) Take the initial dose of this medicine, 3.75mg/23mg, daily for 14 days. 2) After 14 days, take the recommended dose of 7.5mg/46mg for 12 weeks. 3) Assess weight loss. If taking 7.5mg/46mg does not result in a loss of at least 3% of body weight compared with the weight before the start of treatment, discontinue treatment or increase the dose. 4) If the dose is increased, take 11.25mg/69mg daily for 14 days. 5) After 14 days, take 15mg/92mg for 12 weeks. 6) Assess weight loss. If taking 15mg/92mg does not result in a loss of at least 5% of body weight compared with the weight before the start of treatment, discontinue treatment. *The 3.75mg/23mg and 11.25mg/69mg doses are for titration only. Discontinuation Because abrupt discontinuation may cause seizures, gradually discontinue the 15mg/92mg dose by taking it every other day for at least 1 week before completely stopping treatment. Patients with renal impairment Do not exceed 7.5mg/46mg once daily in patients with moderate (creatinine clearance [CrCl] of 30 or more and less than 50 mL/min) or severe (CrCl less than 30 mL/min) renal impairment. Renal impairment is determined by calculating CrCl using the Cockcroft-Gault equation with actual body weight. Patients with hepatic impairment Do not exceed 7.5mg/46mg once daily in patients with moderate hepatic impairment (Child-Pugh score 7-9).

This medication should not be used in conjunction with other appetite suppressants. Safety and efficacy are not established for concomitant use with other weight loss drugs, and thus concurrent administration is not recommended. During pregnancy, this medication may harm the fetus, so it should not be taken. Particularly in early pregnancy, there may be an increased risk of cleft lip and palate in the fetus. If this medication is taken during pregnancy or if pregnancy is confirmed while taking this medication, it should be discontinued immediately, and women of childbearing potential should have regular pregnancy tests before and during treatment and use effective contraception. Topiramate, an ingredient in this medication, can cause serious skin reactions. If symptoms such as rash, blisters, or ulcers appear, the medication should be stopped immediately, and a doctor should be consulted. Pregnant women, patients with glaucoma, hyperthyroidism, those taking certain medications, children under 18, and those with cardiovascular diseases should not take this medication. Patients with kidney or liver dysfunction should use this medication cautiously, and caution is also advised if there are allergic reactions to certain pigment components. This medication can cause a variety of side effects, including altered perception, dizziness, altered taste, insomnia, constipation, dry mouth, headache, altered oral perception, attention disorders, depression, anxiety, nausea, diarrhea, indigestion, gastroesophageal reflux disease, systemic fatigue, irritability, thirst, chest discomfort, blurred vision, eye pain, dry eyes, palpitations, rash, hair loss, hypokalemia, decreased appetite, dysmenorrhea, upper respiratory infections, nasopharyngitis, sinusitis, bronchitis, influenza, and urinary infections. These symptoms mainly occur within the first 12 weeks of treatment but may arise during treatment as well. Moreover, heart rate may increase, so patients with a history of heart disease or cerebrovascular disease should exercise particular caution. If any abnormal symptoms occur while taking this medication, consult a doctor immediately, and it is important to comply with the prescribed dosage and administration.

• Abnormal perception
• dizziness
• abnormal taste
• insomnia
• constipation
• dry mouth
• headache
• sensory loss
• attention deficit
• depression

This medication should be stored in a tightly closed container to protect it from exposure to air or moisture. The appropriate storage temperature is between 1 degree and 30 degrees Celsius, and it should be kept away from overly hot or cold places.

Appearance

A hard capsule with opaque purple top and opaque yellow bottom containing white or almost white granules.

Package unit

28 capsules/bottle