Medication info
Lyrica Capsules 50mg (Pregabalin)

Lyrica Capsules 50mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›50mg / 1 capsule
Manufacturer / importer
한국휴텍스제약(주)
Appearance
A hard capsule with dark blue upper and white lower parts containing white powder
Packaging
30 capsules per bottle
Approval status
Active

MFDS item code 201905365 · Approved 2019.07.29 · Insurance code 649104540

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunct for partial seizures in epilepsy, amelioration of fibromyalgia
Who takes it
Adults · Children
Adult dose
The recommended total daily dosage of this medication, which is pregabalin, is divided into two doses daily and administered orally irrespective of food. 1. Neuropathic Pain - Peripheral Neuropathic Pain: An initial dosage of 150 mg per day may be administered, with possible titration to 300 mg within 3 to 7 days; if needed, it may be increased to a maximum of 600 mg at 7-day intervals. - Central Neuropathic Pain: An initial dosage of 150 mg per day may be administered, with an increase to 300 mg after one week.
Child dose
Due to insufficient safety and efficacy data, administration is not recommended for children under 12 years of age and adolescents aged 12-17.

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunct for partial seizures in epilepsy, amelioration of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used in adults to treat peripheral and central neuropathic pain. It is also effective as an adjunct treatment for partial seizures in epilepsy patients, with or without secondary generalization. Additionally, it is helpful in alleviating pain in fibromyalgia patients. It is used to improve symptoms of various neurological disorders.

How to take

Adult dose

The recommended total daily dosage of this medication, which is pregabalin, is divided into two doses daily and administered orally irrespective of food. 1. Neuropathic Pain - Peripheral Neuropathic Pain: An initial dosage of 150 mg per day may be administered, with possible titration to 300 mg within 3 to 7 days; if needed, it may be increased to a maximum of 600 mg at 7-day intervals. - Central Neuropathic Pain: An initial dosage of 150 mg per day may be administered, with an increase to 300 mg after one week.

Child dose

Due to insufficient safety and efficacy data, administration is not recommended for children under 12 years of age and adolescents aged 12-17.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so if changes in mood or behavior occur during treatment, you must consult a doctor immediately. Do not take this medication if you are allergic to any of its components or have certain genetic lactose metabolism disorders. Diabetic patients may experience weight gain from this medication, which might necessitate a dosage adjustment of blood sugar control medications. If symptoms of angioedema, such as swelling of the face or around the mouth, occur, discontinue the medication immediately and inform healthcare providers. Elderly patients may experience increased dizziness or drowsiness when taking this medication for the first time, hence caution is needed, and care should be taken if these symptoms arise. Some patients may experience blurred vision or changes in eyesight; consulting a doctor is advised if such symptoms occur. Discontinuing this medication suddenly may result in withdrawal symptoms such as insomnia, headache, and anxiety, so it should be tapered off gradually under the direction of a physician. Patients with a history of substance abuse may be at higher risk of abuse of this medication, which requires special caution. Patients with impaired kidney function may need dose adjustments. Patients with severe heart disease should take this medication cautiously, and if symptoms of heart failure appear, they must inform healthcare providers immediately. Caution is needed if this medication is taken concurrently with opioid analgesics, as there may be an increased central nervous system depressant effect. There is a risk of respiratory depression in patients with respiratory disease, kidney disease, and in the elderly; caution is advised when taking this medication. During early pregnancy, there may be a risk of congenital malformations in the fetus, so it is best to avoid using this medication during pregnancy, and women of childbearing age should use effective contraception. Breastfeeding women should consider discontinuing nursing or stopping the medication since it can be transmitted through breast milk. Dizziness and drowsiness may occur while driving or operating machinery, so it's safest to avoid these activities in the early stages of treatment. In case of overdose, symptoms such as altered consciousness, confusion, or seizures may present, requiring immediate medical attention. This medication should be kept out of the reach of children and should not be transferred to other containers for safety.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, facial swelling, swelling around the mouth and upper respiratory tract, sweating, severe swelling (edema), chest tightness, shortness of breath, respiratory distress, respiratory depression, anaphylaxis-like symptoms, Stevens-Johnson syndrome, toxic epidermal necrolysis, mucous membrane syndrome, erythema multiforme, jaundice, liver abnormalities (ALT increase, AST increase, elevated serum creatinine), sudden and severe headache, loss of consciousness

Mild side effects

  • Dizziness
  • drowsiness
  • dry mouth
  • lightheadedness
  • vomiting
  • peripheral edema
  • tremor
  • ataxia
  • memory disturbance
  • attention deficit
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  • constipation
  • gastrointestinal disturbance
  • blood in stool
  • erectile dysfunction
  • increased appetite
  • fatigue
  • weakness
  • gait disturbances
  • sleep disorders
  • insomnia
  • decreased libido
  • anxiety
  • headache
  • diarrhea
  • influenza-like symptoms
  • restlessness
  • excessive sweating

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a tightly sealed container to prevent exposure to air or moisture. The storage temperature should be maintained between 15 and 30 degrees Celsius to safely preserve its efficacy.

Appearance and packaging

Appearance

A hard capsule with dark blue upper and white lower parts containing white powder

Package unit

30 capsules per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.