Klariz 500mg (Clarithromycin)

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half, i.e., 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (Days 1～14), and omeprazole 40mg once daily for 28 days (Days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used by patients who are allergic to certain components. Patients with a history of hypersensitivity to clarithromycin or similar antibiotics should avoid administration. Caution is required for patients taking certain heart-related medications, as this drug may cause cardiac rhythm abnormalities when combined. It should not be administered to patients with severe cardiac arrhythmias, severely impaired liver function, and patients with significantly reduced kidney function. It is also safer for pregnant or breastfeeding women not to use this medication. Avoid administration in patients with central nervous system infections. This medication contains lactose, so it is not suitable for patients with lactose intolerance. Patients with poor liver or kidney function, heart disease, or elderly patients should use this medication with more caution. Drug interactions may occur if other antibiotics or specific medications are taken, so consultation with a physician is necessary. This medication can rarely cause serious allergic reactions or adverse reactions involving the liver, kidneys, skin, or nervous system. If any abnormal symptoms occur, immediate medical attention is required. Prolonged or high-dose use may cause hearing loss or tinnitus, and in this case, administration should be stopped. If gastrointestinal disorders, such as diarrhea or abdominal pain, worsen during antibiotic use, administration should be stopped immediately, and medical attention should be sought. This medication is likely to interact with other drugs, so all medications being taken should be reported to healthcare professionals, and blood tests or monitoring may be necessary. Overdose may cause gastrointestinal disorders or central nervous system symptoms, so immediate emergency intervention should be sought. When stored, it should be kept in a sealed container that blocks light and at room temperature, avoiding refrigeration.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, indigestion, abdominal pain, discomfort, gas retention, diarrhea, oral erosions, upper abdominal pain, thirst, tooth discoloration, pancreatitis, amylase increase, dysgeusia, appetite loss, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, chest X-ray abnormalities, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, ageusia, anosmia, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, paresthesia, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increase in liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, AST elevation, ALT elevation, γ-GTP elevation, LDH elevation, ALP elevation, total bilirubin increase, serum creatinine increase, BUN increase, interstitial nephritis, renal failure, rhabdomyolysis, stomatitis, cheilitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, increased serum creatinine, increased blood urea, renal failure, nephritis, injection site venous thrombosis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine color abnormality

This medication should be stored in a sealed container that blocks light, and the temperature should be kept between 15 degrees and 30 degrees Celsius. Storing it this way will help maintain the effectiveness and safety of the medication.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 200 tablets/bottle