Intrac Tablet 6.25 mg (Carvedilol)

Adult dose

Do not increase the dose or discontinue treatment without a doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If an increase is needed, increase to 25 mg twice daily. The maximum single dose is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients In some elderly patients, 12.5 mg once daily may be sufficient. If the response is inadequate after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine per dose, twice daily orally, then administer 25 mg per dose twice daily orally. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to up to 50 mg per dose twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard treatment regimen (conventional therapy for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial treatment is 3.125 mg of this medicine per dose, twice daily orally for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg per dose twice daily for 2 weeks, then to 12.5 mg per dose twice daily for 2 weeks, and then to 25 mg per dose twice daily. 2) Increase the dose gradually after taking each dose for at least 2 weeks, up to the dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less, and 50 mg per dose twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended that the medicine be taken with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be used in certain patients. For example, patients with a history of allergy to this drug or its ingredients, patients in cardiogenic shock, patients with very slow heart rates or conduction problems, patients with cor pulmonale, patients with metabolic abnormalities due to diabetes, patients with severe heart function impairment, patients with asthma or chronic lung disease, and women who are pregnant or breastfeeding may be at risk when taking this drug. Additionally, patients with diabetes or those sensitive to allergic reactions, certain cardiovascular diseases, and patients with severely impaired kidney or liver function should use this medication with caution. Especially in the elderly, patients with low blood pressure, or those taking certain medications, extra caution is necessary. While taking this medication, symptoms such as dizziness, headaches, and fatigue may occur, and there is also a risk of a slowed heart rate or excessively low blood pressure. Patients with heart failure or conduction disorders may experience worsening conditions, so regular check-ups are required. Also, if kidney function is impaired, deterioration in kidney function may occur, and patients with respiratory diseases may experience worsened dyspnea. Gastrointestinal symptoms such as nausea, diarrhea, and abdominal pain may appear, as well as skin rashes or allergic reactions. This drug can also affect liver function, so any signs of liver dysfunction should be immediately reported to healthcare professionals. Occasionally, decreased tear production, dry mouth, urination disorders, and sexual dysfunction have also been reported. This drug requires regular cardiac function tests during long-term use, and sudden discontinuation can worsen heart-related symptoms, so the dosage must be gradually reduced according to the physician's instructions. Particularly, caution is needed while driving or operating dangerous machinery as dizziness or drowsiness may occur. Furthermore, this drug can interact with various medications, so if taking other drugs, healthcare providers should be informed. Women who are pregnant or breastfeeding should avoid taking this drug, and the safety and effectiveness in children or adolescents under 18 years old have not been established. In the elderly, drug concentration may increase due to decreased liver function, so it is advisable to start at a low dose and administer with caution. In case of overdose, symptoms such as lowered blood pressure, decreased heart rate, worsened heart function, dyspnea, and altered consciousness may occur, and immediate contact with a medical institution should be made for appropriate treatment. Finally, this drug can change color when exposed to light, so it should be stored in opaque containers and kept out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication may be sensitive to light, so it should be stored in an airtight container that protects it from light. Additionally, it is best to keep it at room temperature between 1°C and 30°C.

Appearance

Pale yellow round film-coated tablet

Package unit

30 tablets/bottle