Neboraxin Tablet 500mg (Levofloxacin Hydrate)

Adult dose

Typically, for adults, levofloxacin is administered orally at a dose of 250 to 750 mg once daily. 1. For patients with normal renal function (creatinine clearance over 80 mL/min) - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10 to 14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days of treatment - Acute sinusitis: 10

This drug is a fluoroquinolone antibiotic and may cause serious side effects such as tendon-related disorders (tendinitis or tendon rupture), peripheral neuropathy, central nervous system symptoms, etc. It should not be used in patients with myasthenia gravis due to the risk of exacerbating symptoms. The drug is used for the treatment of acute bacterial sinusitis, acute exacerbation of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media, but it is recommended to administer only when no other treatment options are available. Elderly patients, patients with reduced renal function, and those taking corticosteroids are at increased risk for tendon rupture, necessitating caution. Furthermore, this drug may induce seizures, so it should be used with caution in patients with central nervous system disorders or a history of seizures. Severe allergic reactions or skin reactions may occur due to hypersensitivity, thus administration should be stopped immediately if such symptoms manifest. Psychological symptoms such as anxiety, depression, hallucinations, confusion, etc., may occur, so any unusual symptoms should prompt consultation with medical personnel. Patients with heart disease should be cautious as it can influence cardiac function, leading to arrhythmias or QT interval prolongation. It may affect renal and liver function, so patients with related conditions should undergo regular testing. This drug may cause gastrointestinal disturbances, muscle pain, skin rashes, etc., so it is crucial to notify medical personnel immediately if symptoms occur. It should not be administered to pregnant women, nursing mothers, or growing adolescents under 18 years of age, and elderly patients may require dosage adjustments due to the risk of renal impairment and hepatotoxicity. This drug may interact with other medications, particularly antacids, iron supplements, calcium supplements, hypoglycemics, and anticoagulants, so consultation with a physician or pharmacist is essential for those taking these agents. In cases of overdose, symptoms of central nervous system abnormalities and cardiac issues may arise, necessitating immediate medical treatment, as it is not removed through hemodialysis. This drug should be protected from strong sunlight and artificial UV exposure, and if pain or inflammation occurs during exercise, administration should cease, and rest should be taken.

Serious side effects

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of severe myasthenia gravis, shock, severe allergic reactions (hives, severe swelling, chest tightness, respiratory distress, cold sweat, pallor), severe skin reactions (severe rashes with high fever, blisters, skin peeling, pain in oral/eye mucosa), seizures, convulsions, altered consciousness, visual disturbances, paralysis, neurological symptoms, acute kidney failure, liver abnormalities (elevated liver enzymes, acute

Mild side effects

Dizziness, headache, insomnia, tremors, anxiety, depression, psychiatric reactions (hallucinations, paranoia, nervousness, delirium, disorientation, impaired attention, nightmares, etc.), agitation, confusion, visual and auditory impairments, taste and smell disturbances, auditory hallucinations, palpitations, QT interval prolongation, arrhythmia, elevated BUN and serum creatinine, leukopenia, erythrocytopenia, hemoglobin reduction, decreased hematocrit, eosinophilia, anemia, hemolysis

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Pink rectangular film-coated tablet

Package unit

- - 30 tablets/bottle, - - 100 tablets/bottle