Ciplox Tablets (Ciprofloxacin Hydrochloride Hydrate)

Adult dose

For adults, the usual dose of ciprofloxacin is 250 to 500 mg per dose, administered orally twice a day between meals. For severe complicated infections, the dose may be increased to 750 mg twice a day. In the case of acute infections, treatment is typically for 5 to 10 days, with at least 3 additional days of treatment after symptoms have resolved. For patients with renal impairment: 1) Creatinine clearance > 50 mL/min: administer the usual dose.

This medication can cause serious adverse reactions such as tendinitis or tendon rupture, peripheral neuropathy, and central nervous system effects, so administration must be stopped immediately if such symptoms appear. In particular, patients with severe myasthenia gravis may experience worsening symptoms due to this medication and should not use it. This drug is used to treat specific bacterial infections and should be used cautiously and only when no alternative treatment options are available. Elderly patients, renal impairment patients, and patients taking corticosteroids are at increased risk of tendon rupture and should avoid combination therapy. Pregnant women, breastfeeding women, adolescents under 18, and patients with epilepsy should not use this medication. Additionally, the risk of adverse effects increases when taken with certain medications such as tizanidine or ketoprofen, so these should not be combined. Care should be taken when using this drug in patients with severe renal impairment, seizure history, elderly patients, or patients with central nervous system disorders. This medication can cause various adverse reactions, and caution is needed as side effects such as skin rash, gastrointestinal disorders, neurological disorders, liver function abnormalities, musculoskeletal pain, and kidney problems have been reported. Particularly, if diarrhea or abdominal pain occurs, there may be a risk of serious intestinal conditions such as pseudomembranous colitis, and consultation with a physician is necessary. This medication may cause hypersensitivity reactions to sunlight, so strong sunlight or artificial UV exposure should be avoided, and administration should be stopped if any unusual symptoms occur. Additionally, if sensory abnormalities appear, patients should consult a specialist. This medication could affect driving or machine operation capabilities, so caution is advised, especially when taken with alcohol. Patients with heart-related issues or those at risk of QT interval prolongation should exercise additional caution when using this medication. Diabetic patients requiring blood sugar control should monitor for fluctuations in blood sugar and check their levels regularly. This medication often has many drug interactions, so it is crucial to consult a physician or pharmacist when taken with theophylline, warfarin, diabetes medications, and immunosuppressants. Pregnant or nursing women should either avoid this medication or stop breastfeeding, and it is not to be used in growing children or adolescents. Elderly patients may have increased drug concentrations due to declining kidney function, thus dosage and administration intervals should be adjusted. In case of overdose, renal function should be monitored carefully, and appropriate treatment should be given if necessary. Medications should be stored in a tightly sealed container to prevent air exposure and kept at room temperature between 1 and 30 degrees Celsius. Proper storage can prolong the drug's efficacy.

Serious side effects

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, worsening of myasthenia gravis, anaphylaxis, shock, severe allergic reactions, serumsickness-like reactions, antibiotic-associated colitis, bone marrow depression, hemolytic anemia, agranulocytosis, pancytopenia, syndrome of inappropriate antidiuretic hormone secretion, liver function test abnormalities, jaundice, hepatic impairment, hepatitis, cholestatic jaundice, hepatic necrosis, skin and mucous membrane syndrome, Stevens-Johnson syndrome.

Mild side effects

• Headache
• dizziness
• sleep disorders
• taste disorders
• insomnia
• confusion
• disorientation
• emotional instability
• abnormal dreams
• depression

This medication should be stored in a sealed container to prevent air ingress and should be kept at room temperature between 1 and 30 degrees Celsius. Storing it this way helps to maintain the drug's effectiveness for a longer duration.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle