Neobit 100 mg (Levofloxacin Hydrate)

Adult dosage

Typically, for adults, levofloxacin is administered at a dose of 100 mg orally 2-3 times a day. For severe cases or insufficient effects, the dose is increased to 200 mg, taken 3 times a day. Dosing may be adjusted based on age and symptoms.

This medicine is a fluoroquinolone antibiotic used to treat certain bacterial infections. However, when taking this medication, there is a risk of tendon issues such as tendinitis or tendon rupture, peripheral neuropathy, and central nervous system adverse effects. In particular, patients with myasthenia gravis should avoid this medication as symptoms can worsen. Additionally, this medicine should only be used when there are no other treatment options for its limited indications such as acute bacterial sinusitis, acute exacerbation of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media. There is an increased risk of tendon rupture in the shoulder, hand, and Achilles tendon during the use of this medicine, particularly in elderly patients, patients with impaired kidney function, and those taking corticosteroids. Therefore, any pain or inflammation should prompt an immediate cessation of the medication and rest. Patients with myasthenia gravis should be especially careful due to the neuromuscular blocking effects of this medicine, which can worsen their symptoms. Patients with a history of hypersensitivity to this medicine or similar classes of drugs, or with history of tendinitis or tendon rupture related to these medications should not use it. It is also not safe for children in the growth period under 18, as well as pregnant or breastfeeding women, and patients with epilepsy. Patients with significantly impaired kidney function, central nervous system disorders or seizure history, elderly patients, and diabetic patients should use this medicine cautiously. Blood glucose levels should be monitored closely, especially when used in conjunction with blood glucose-lowering medications, as changes can occur. This medication can rarely cause shock, severe allergic reactions, neuropsychiatric adverse effects, abnormal heart rhythm, kidney and liver dysfunction, blood anomalies, gastrointestinal disturbances, musculoskeletal issues, and severe skin reactions. If any unusual symptoms arise, immediate consultation with a healthcare provider is recommended. Additionally, during the use of this medicine, exposure to strong sunlight or artificial UV light should be avoided, and care should be taken when driving or operating machinery due to potential dizziness or drowsiness. This medicine can interact with other medications, so particularly when taking antacids, iron, calcium, non-steroidal anti-inflammatory drugs, anticoagulants, theophylline, or diabetes medications, consultation with a physician or pharmacist is essential. It is advisable not to take this medicine during pregnancy or breastfeeding, and it is not administered to children. Elderly patients may experience increased drug concentration due to kidney function decline and a risk of hepatotoxicity, necessitating dose adjustment and monitoring. In case of overdose, symptoms of central nervous system disturbances and cardiac electrical abnormalities may manifest, requiring immediate medical attention for appropriate treatment.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, breathing difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered mental status, visual disturbances, paralysis, urination.

Mild side effects

Insomnia, dizziness, headache, tremor, anxiety, depression, psychotic reactions (hallucinations, paranoia, irritability, delirium, disorientation, attention disorders, nightmares), agitation, confusion, visual and auditory disturbances, taste and smell disorders, auditory hallucinations, sensory disturbance, sensory loss, weakness, palpitations, QT interval prolongation, arrhythmias, increased BUN and serum creatinine, leukopenia, anemia, decreased hemoglobin, decreased hematocrit.

This medicine should be stored in a tightly closed container to prevent air ingress, and it is best kept at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

White to off-white film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle