Cefaclor Capsules (Cefaclor Hydrate)

Adult dose

As cefaclor hydrate, take 250 mg (potency) orally every 8 hours. In severe infections (such as pneumonia) and infections with low sensitivity, the dose may be doubled. For acute gonococcal urethritis, this drug 3g and probenecid 1g should be administered together in a single dose.

Child dose

Administer 20 mg/kg (potency) divided every 8 hours. In cases of severe infections, otitis media, and infections with low sensitivity, administer 40 mg/kg (potency) daily, with a maximum dose of

This drug is an antibiotic that kills bacteria by binding to specific proteins, interfering with the synthesis of bacterial cell walls. It should not be used in patients who have previously experienced severe allergic reactions or shock due to this drug. Those with allergies to this drug or similar class antibiotics should also avoid it. Patients allergic to penicillin-class drugs or those prone to allergic reactions such as asthma, rashes, or hives must be more cautious when using this drug. Patients with severely impaired kidney function, those who have difficulty swallowing, elderly patients, and those in poor general condition should be carefully monitored for the risk of bleeding due to vitamin K deficiency. Patients with a history of gastrointestinal diseases, especially colitis, should also use this drug with caution. Rarely, this drug can cause shock or severe allergic reactions; if symptoms occur while using it, one should immediately stop taking the drug and seek appropriate treatment. Severe skin reactions such as Stevens-Johnson syndrome, characterized by severe rashes or blisters, can also occur, so caution is advised. Adverse effects such as blood abnormalities, liver function abnormalities, and renal impairment may occur, necessitating regular testing. Gastrointestinal symptoms, including abdominal pain, diarrhea, nausea, and vomiting, may occur, and severe colitis can develop, so consultation with medical personnel is needed if symptoms arise. Respiratory symptoms may include fever, cough, and difficulty breathing, and if these symptoms appear, the drug should be discontinued and treatment should be sought. The central nervous system may be affected, leading to dizziness, anxiety, insomnia, and hallucinations, which may occur rarely. Taking this drug may lead to disruptions in the oral flora, causing oral inflammation or candidiasis. Deficiency symptoms of vitamin K and B group may appear rarely; hence, one should be cautious in the presence of bleeding tendencies or neurological symptoms. This drug may interact with other medications, particularly those affecting the kidneys, anticoagulants, and oral contraceptives, so consultation with a physician is necessary when co-administering. Women who are pregnant or breastfeeding should use this drug cautiously, as its safety has not been fully established. It is advisable to avoid using this drug in newborns under 1 month of age, as its safety and efficacy have not been established. Elderly patients may experience more pronounced side effects due to decreased bodily functions; thus, dosage adjustment and monitoring of their condition are essential. Finally, when using this drug, it is crucial to verify the sensitivity of the infection-causing bacteria to prevent the occurrence of resistant strains and to administer the drug for the necessary minimum duration.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• shock
• systemic flushing
• edema
• respiratory distress
• angioedema
• sensory disturbances

Mild side effects

• Rash
• itching
• fever
• lymphadenopathy
• joint pain
• serum sickness-like reaction
• agranulocytosis
• granulocytopenia
• anemia
• thrombocytopenia

This drug should be stored in a tightly closed container to avoid exposure to air or moisture. It is best stored at room temperature between 1°C and 30°C. This will help maintain the drug's efficacy.

Appearance

A hard capsule with a purple upper part and a white lower part filled with pale yellow powder

Package unit

30 capsules/bottle, 300 capsules/bottle