Medication info
Lyrica Capsule 75 mg (Pregabalin)

Lyrica Capsule 75 mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›75mg / 1 capsule
Manufacturer / importer
건일바이오팜주식회사
Appearance
Hard capsule with upper reddish-brown and lower white color containing white or light yellow powder
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201903451 · Approved 2019.05.28 · Insurance code 073000620

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjuvant effect for partial seizures in epilepsy, improvement of fibromyalgia
Who takes it
Adults · Children
Adult dose
This drug, which contains pregabalin, is administered orally divided into two doses per day, regardless of food. 1. Neuropathic Pain 1) Peripheral Neuropathic Pain - Starting Dose: 150 mg per day - Can be increased to 300 mg per day after 3 to 7 days - Can be further increased to a maximum of 600 mg per day as needed at intervals of 7 days 2) Central Neuropathic Pain - Starting Dose:
Child dose
There is insufficient safety and efficacy data for children under 12 years of age and adolescents aged 12 to 17 years, so use is not recommended.

Ingredients

Manufacturer
건일바이오팜주식회사

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjuvant effect for partial seizures in epilepsy, improvement of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used to relieve peripheral and central neuropathic pain in adults. It is also effective as an adjunctive treatment for partial seizures in patients with epilepsy, whether accompanied by secondary general symptoms or not. Additionally, it helps in the treatment of fibromyalgia. Thus, it is used to improve various neurological disorders and pain symptoms.

How to take

Adult dose

This drug, which contains pregabalin, is administered orally divided into two doses per day, regardless of food. 1. Neuropathic Pain 1) Peripheral Neuropathic Pain - Starting Dose: 150 mg per day - Can be increased to 300 mg per day after 3 to 7 days - Can be further increased to a maximum of 600 mg per day as needed at intervals of 7 days 2) Central Neuropathic Pain - Starting Dose:

Child dose

There is insufficient safety and efficacy data for children under 12 years of age and adolescents aged 12 to 17 years, so use is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so patients should be closely monitored for signs of depression, mood changes, or abnormal behavior while taking it. Patients allergic to any component of this medication or those with specific genetic metabolic disorders should not take it. Diabetic patients should be cautious as weight gain may require adjustments to their blood sugar medications. If serious allergic reactions, such as angioedema, occur, the medication should be stopped immediately and healthcare providers should be consulted. Elderly patients are at risk of falls due to dizziness or drowsiness, and therefore should be particularly cautious during the initial dosing. Some patients may experience blurred vision or changes in vision; if this occurs, consult a physician. Discontinuation of the medication may lead to withdrawal symptoms such as insomnia, headache, and anxiety, hence it is advisable to taper off gradually under medical guidance. There is a risk of drug abuse; thus, patients with a history of mental illness or substance abuse should be especially monitored for unusual behavior. Patients with impaired renal function may require dose adjustments. Patients with cardiovascular diseases should also use this medication cautiously. Caution is warranted when taking this medication alongside opioid analgesics as it may enhance central nervous system depressant effects. Patients with respiratory diseases or renal impairment, as well as the elderly, may face a risk of respiratory depression and may require dose adjustments. In early pregnancy, this medication should be avoided due to the risk of fetal malformation and females of childbearing potential should use effective contraception. During breastfeeding, this medication can be passed into breast milk, so careful consideration should be given regarding the continuation of breastfeeding and the necessity of treatment. Be cautious while driving or operating machinery due to the risk of accidents caused by dizziness or drowsiness. This medication can cause severe skin reactions, and if skin rashes or edema occur, it should be discontinued immediately. In cases of overdose, symptoms such as confusion, drowsiness, and depression may occur, and blood dialysis may be necessary if required. Special caution is needed for children and the elderly when taking this medication, and children should be kept out of reach.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities associated with coughing and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • disorientation
  • irritability
  • depression
  • contentment
  • reduced libido
  • insomnia
  • depersonalization
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  • sexual hypersensitivity
  • restlessness
  • anxiety
  • mood swings
  • emotional lability
  • difficulty finding the right words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • motor coordination abnormalities
  • balance disorders
  • memory loss
  • attention deficits
  • memory deficits
  • tremors
  • speech disorders
  • sensory abnormalities
  • sensory deficits

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly closed container. It is recommended to keep the storage temperature between 15 and 30 degrees Celsius. Doing so can help preserve the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

Hard capsule with upper reddish-brown and lower white color containing white or light yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.