Megasimba Tablets 10/20 Milligrams

Adult dose

This medication is administered once daily in the evening, regardless of meals. For patients with primary hypercholesterolemia, the dosage range is 10/10mg to 10/40mg, with the generally recommended starting dose being 10/20mg once daily. Patients requiring less reduction in LDL cholesterol may start with 10/10mg once daily. The recommended dosage for patients with homozygous familial hypercholesterolemia is 10/40mg once daily.

This medication is used to lower blood cholesterol levels. Caution is necessary as muscle abnormalities may occur while taking this medication. If muscle pain or weakness arises, notify a doctor immediately, and discontinue use if symptoms are severe. This medication may affect liver function, so it should not be administered in cases of liver disease or elevated liver function test results. Pregnant or nursing women should not take this medication, and women of childbearing age must consider the possibility of pregnancy when using it. The risk of muscle abnormalities may increase when taken with certain medications, so inform your physician or pharmacist if you are taking other drugs. Elderly patients, patients with impaired kidney function, and patients with hypothyroidism may be at increased risk of side effects and require caution. Regular blood tests to monitor liver function and muscle condition are recommended during treatment. There is no specific antidote for overdose; treatment will be symptomatic. It is advisable to limit the intake of certain foods, such as grapefruit juice, while taking this medication. Finally, if new symptoms or adverse reactions occur during therapy, consult with medical personnel immediately.

Serious side effects

Myopathy, rhabdomyolysis, angioedema, rash, pancreatitis, cholelithiasis, cholecystitis, anaphylaxis, angioedema, urticaria, toxic epidermal necrolysis, Stevens-Johnson syndrome, hepatitis, cholestatic jaundice, cirrhosis, fulminant hepatic necrosis, hepatocellular carcinoma, fatal hepatic failure, severe edema, chest tightness, dyspnea, asthma attacks, respiratory difficulties with cough and fever, jaundice of the skin or eyes, generalized malaise.

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory infection
• muscle pain
• limb pain
• fatigue
• nausea
• abdominal pain
• constipation

Store this medication in a tightly closed container to protect from air and moisture. Additionally, it is important to maintain the medication's efficacy by storing it at a temperature between 1 and 30 degrees Celsius.

Appearance

White to off-white, double convex, rectangular tablets

Package unit

30 tablets (10 tablets/PTP*3)