Clarith Tablet 250 mg (Clarithromycin)

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years and older: same as adults For children under 12 years, use clarithromycin dry syrup.

This medicine should not be used in certain patients. For example, patients with an allergy to the ingredients of this medication or who have hypersensitivity to macrolide antibiotics should avoid taking it. Additionally, patients with severe heart arrhythmias, significantly impaired liver or kidney function, and pregnant or nursing women should not take this medication. Caution is required when using this drug in patients with weakened liver and kidney function or heart diseases, and elderly patients should also take it carefully. During use, various side effects such as allergic reactions, indigestion, skin rashes, heart arrhythmias, liver function abnormalities, and kidney problems can occur, so symptoms should be closely monitored. If severe allergic reactions, skin diseases, persistent diarrhea, hepatitis symptoms, or muscle pain occur, immediately stop taking it and consult a healthcare professional. This medication may have a high potential for drug interactions, particularly when taken with medications that affect the heart, affect blood coagulation, or affect liver and kidney function. Pregnant or nursing women should not take this drug; if it is unavoidable, breastfeeding should be stopped. Safety has not been sufficiently confirmed for children, so caution is required when used. During the use of this drug, dizziness or confusion may occur while driving or operating machinery, so caution is advised. Overdose may lead to gastrointestinal disturbances or mental instability symptoms, so the dosage must be strictly followed, and any abnormal symptoms should be immediately reported to a healthcare professional. This medication should not be refrigerated and should be stored in a special container that blocks light, avoiding direct sunlight.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, hives, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, cramp-like upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, delirium, disorientation, hallucinations, psychosis, depersonalization, tonic-clonic convulsions, clonic spasm syndrome, loss of consciousness seizures, tremor, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, anorexia, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, fatigue, elevated CPK, elevated serum myoglobin, elevated urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de Pointes, malaise, headache, taste disorder, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, hearing impairment, hypoglycemia, purpuric rash, acute generalized eruptive pustulosis, muscle cramping, musculoskeletal rigidity, myopathy, elevated blood urea nitrogen, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase, elevated lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, cardiac arrest, atrial fibrillation, prolonged QT interval on electrocardiogram, ectopic beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, vesicular dermatitis, papular rash, acne, Henoch-Schönlein purpura, musculoskeletal and connective tissue disorders

This drug is sensitive to light and should be stored in a special container that shields it from light. Additionally, it is important to store it at room temperature between 15 degrees and 30 degrees to preserve its effectiveness.

Appearance

Yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle