Clarithite 500mg Tablet (Clarithromycin)

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine 3 times daily for 14 days with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for an additional 14 days. In other words, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years or older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, it should not be used in patients who have allergies to any of its components or had allergic reactions to similar classes of antibiotics. Additionally, patients with severe impairment of heart function or liver and kidney function should not use this medication. It is also advisable to avoid this medication in pregnant or breastfeeding women. While taking this medication, caution is needed as it may interact with other drugs, especially those that affect the heart or those that have an impact on the liver and kidneys. This medication may cause side effects, so if you experience symptoms such as allergic reactions, digestive disturbances, skin rashes, liver function abnormalities, kidney function abnormalities, or central nervous system symptoms, consult a physician immediately. If you experience severe allergic reactions or symptoms of cardiac arrhythmia, discontinue administration immediately and seek treatment. To prevent the development of resistant bacteria, it is important to take this medication only for the necessary duration. Additionally, caution should be exercised regarding bacterial flora alternation or the proliferation of resistant bacteria with prolonged or repeated use. It is recommended that pregnant or breastfeeding women avoid this medication, and if it is absolutely necessary to take it, they should consult a specialist. Elderly patients or those with impaired kidney and liver function may need dosage adjustments, so they should follow medical personnel's instructions. This medication may cause dizziness or confusion when driving or operating machinery, so caution is advised. In the case of overdose, gastrointestinal disturbances or central nervous system symptoms may occur; therefore, seek appropriate treatment from a medical institution immediately. During the course of taking this medication, it is important to monitor for abnormalities through regular blood tests and liver and kidney function tests. Finally, this medication must be stored properly, with dry syrup not refrigerated but kept at room temperature.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rashes, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal lesions, epigastric pain, dry mouth, tooth discoloration, pancreatitis, increased amylase, taste disturbance, appetite loss, constipation, fecal discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, anosmia, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremors, paresthesia, behavior changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, atrial fibrillation, ECG QT prolongation, premature contractions, palpitations, cardiac arrest, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, distention, tongue discoloration, hyperhidrosis, bullous eruption, acne, Henoch-Schonlein purpura, acute generalized pustular exanthema, muscle cramping, musculoskeletal rigidity, myalgia, myopathy, elevated blood urea nitrogen, venous inflammation at injection site, pain at injection site, inflammation at injection site, malaise, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, psychotic disorders, confusion state, abnormal dreams, headache, loss of consciousness, movement disorders, non-vestibular dizziness, drowsiness, tremor, convulsions, abnormal olfaction, vestibular dizziness, hearing impairment, hearing loss, hypoglycemia, taste distortion, reversible hearing loss, dysesthesia, arthralgia, olfactory disorder

This medication is sensitive to light, so it should be stored in a container that can block light. Additionally, to maintain efficacy, it should be stored in a cool room temperature, specifically between 15 to 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle