Vimpro Tablets 150 mg (Lacosamide)

Adult dose

This medication should be taken twice daily. The recommended initial dose is 50mg twice daily, and after 1 week it should be increased to 100mg twice daily. Depending on clinical response and tolerability, the maintenance dose may be increased each week by 50mg twice daily, up to the maximum recommended dose of 400mg/day (200mg twice daily). If treatment with this medication must be discontinued, gradual dose reduction is recommended. (e.g., gradually reduce the daily dose by 200mg each week) This medication may be taken with or without food. 1. Patients with renal impairment No dosage adjustment is required in patients with mild or moderate renal impairment (CLCR>30mL/min). A maximum dose of 300mg/day is recommended for patients with severe renal impairment (CLCR≤30mL/min) and those with end-stage renal disease. Since this medication is removed from plasma by hemodialysis, hemodialysis patients are recommended to receive an additional dose of up to 50% of the single dose immediately after hemodialysis. Treatment of patients with end-stage renal disease should be undertaken with caution because clinical experience is limited and a metabolite (whose pharmacological activity is unknown) may accumulate. Dosage adjustments should be made cautiously in all patients with renal impairment. 2. Patients with hepatic impairment Dosing should be undertaken with caution in patients with hepatic impairment. A maximum dose of 300mg/day is recommended for patients with mild or moderate hepatic impairment. Use is not recommended in patients with severe hepatic impairment. 3. Older adults Dose reduction is not required in older adults. Although experience with lacosamide use in older adults with epilepsy is limited, decreased renal clearance and increased AUC are associated with age and should be taken into consideration in older adults. (See the section on ‘Patients with renal impairment’)

Child dose

Children and adolescents under 16 years of age: Use in these age groups is not recommended because data on the safety and efficacy of this medication in children and adolescents under 16 years of age are unavailable.

This medication is used for the treatment of neurological disorders such as epilepsy. During treatment, there may be an increased risk of suicidal thoughts or behaviors, so any symptoms of depression or mood changes should be reported to a doctor or pharmacist immediately. Do not take this medication if you are allergic to any of its components. Dizziness may occur during use, which increases the risk of falls or accidents, so extra caution is advised when starting treatment. Patients with heart disease or conduction abnormalities should undergo an ECG before taking this medication, and must report any cardiac symptoms immediately to healthcare professionals. Consult healthcare professionals immediately if you experience symptoms of depression, abnormal mood, behavioral changes, or suicidal thoughts. This medication can rarely cause serious allergic reactions, so if you experience a rash, fever, or other unusual symptoms, discontinue use and seek medical attention promptly. The most common side effects include dizziness, headache, nausea, double vision, and if symptoms are severe, it may be necessary to consult a doctor for dosage adjustment. Caution is advised while driving or operating machinery because dizziness or blurred vision may occur. There may be interactions with other medications, so you should inform healthcare professionals about any medications you are taking. No special dosage adjustment is needed for elderly patients, but they should consider their physical condition when taking this medication. Use is not recommended for children or adolescents under the age of 16, as safety and efficacy have not been established for this age group. Women who are pregnant or planning to become pregnant should consult a doctor before taking this medication, and caution is needed if breastfeeding since the medication can be passed through breast milk. Overdose may cause dizziness, nausea, vomiting, etc., and there is no specific antidote available; therefore, immediate medical treatment is necessary. This medication may potentially lead to psychological dependence, so it should be taken precisely as directed by a physician. Store in a place out of reach of children and do not transfer to another container.

suicidal thoughts, suicidal behavior, depression, abnormal changes in mood and behavior, dizziness, ataxia, prolonged PR interval, second-degree or higher atrioventricular block, atrial fibrillation, atrial flutter, palpitations, rapid or irregular heartbeat, shortness of breath, multisystem hypersensitivity, rash, eosinophilia, hepatitis, nephritis, lymphadenopathy, myocarditis, headache, nausea, diplopia, confusion, insomnia, mood changes, depressed mood, cognitive impairment, eye twitching, balance disorder, cooperative disorder, memory impairment, tremors, drowsiness, dysarthria, attention deficit, sensory impairment, paresthesia, cerebellar syndrome, blurred vision, vertigo, tinnitus, vomiting, constipation, gastric distension, dyspepsia, dry mouth, diarrhea, oral sensation reduction, muscle cramps, itching, gait disturbance, asthenia, fatigue, hypersensitivity, feeling intoxicated, fever, falls, skin laceration, contusion, neutropenia, anemia, atrioventricular block, syncope, bradycardia, abnormal liver function tests, agranulocytosis, drug hypersensitivity reactions, euphoria, suicide attempt, aggression, anxiety, psychotic disorder, hallucinations, cardiac asystole, cardiac arrest, death, toxic epidermal necrolysis, Stevens-Johnson syndrome, angioedema, urticaria, seizures, ataxia, sedation, hair loss, blisters, early satiety, weight gain, decreased appetite, urinary incontinence, hiccups, rigidity-tonic seizures, status epilepticus

This medication should be stored in a tightly sealed container to prevent air or moisture exposure, and it is safe to store at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the efficacy of the medication.

Appearance

Peach-colored oval film-coated tablet

Package unit

30 tablets/bottle, 120 tablets/bottle, 56 tablets (14 tablets/PTP packaging x 4)