Dae Woo Cefradin Capsule (Cefradine Hydrate)

Adult dose

○ Adults 1) Skin and soft tissue infections, respiratory tract infections: Depending on severity, administer 250mg～500mg (potency) of cefradine per dose 4 times daily, or 500mg～1g (potency) twice daily, orally. 2) Urinary tract infections: For uncomplicated urinary tract infections, administer 500mg (potency) per dose twice daily. For severe urinary tract infections, administer 500mg (potency) per dose 4 times daily or 1g (potency) per dose twice daily. Severe infections may also require an extended treatment period and intensive treatment. ○ Patients with renal impairment 1) In patients not undergoing hemodialysis, administer as follows. Creatinine clearance (mL/min) / dose (mg) / dosing interval (hours) >20 / 500 / 6～12 15～20 / 250 / 12～24 10～14 / 250 / 24～40 5～9 / 250 / 40～50 <5 / 250 / 50～70 2) In patients undergoing chronic, intermittent hemodialysis, administer an initial dose of 250mg (potency) at the start of hemodialysis, followed by 250mg (potency) 6～12 hours later and 36～48 hours later. Then administer 250mg at the next hemodialysis session (only if at least 30 hours have elapsed since the most recent dose). Dosage may be adjusted appropriately according to age and symptoms.

Child dose

○ Children: Administer 25～50mg (potency) per kg of body weight per day orally in 2～4 divided doses. For otitis media, administer 75～100mg (potency) per kg of body weight per day in 2～4 divided doses. Do not exceed 4g (potency) per day or the adult dose. It is preferable not to administer to infants 9 months of age or younger.

This medication should not be used in patients who have experienced severe allergic reactions or shock from this medication in the past. Patients who have had allergic reactions to this medication or to cephalosporin antibiotics should generally not use it, but if necessary, must use it with great caution. Patients who are allergic to penicillin antibiotics should also be careful when using this medication. If you or anyone in your family has a tendency to frequently experience allergic reactions such as asthma, skin rashes, or hives, careful consideration is needed before use. Patients with severely impaired kidney function should use this medication with particular caution, and regular monitoring is necessary. Patients who have difficulty taking medications orally, those with inadequate nutritional intake, elderly patients, and those in poor general condition should be closely monitored for signs of vitamin K deficiency. This medication contains the dye Yellow No. 5, so patients with allergies or sensitivity to this component should use it cautiously. If dizziness, oral discomfort, shortness of breath, sweating, or ringing in the ears occur while using this medication, discontinue use immediately and consult a healthcare professional. If allergic symptoms like skin rashes, hives, itching, red spots, fever, lymphadenopathy, or joint pain appear, the medication should be stopped, and appropriate treatment should be sought. In cases of abdominal pain or diarrhea, especially if there is blood in the stools, it may indicate severe colitis; thus, discontinue the medication immediately and inform a healthcare professional. Gastrointestinal symptoms such as nausea, vomiting, heartburn, decreased appetite, and abdominal distension may occur. If symptoms of dyspnea, cough, or fever present, it may indicate pneumonia or pulmonary infiltrates; discontinue the medication immediately and seek treatment. There may be a decrease in white blood cell or platelet counts on blood tests, so regular monitoring is necessary. Rarely, severe skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis may occur, so the skin condition should be carefully monitored. Liver function tests may show elevated levels, and hepatitis or jaundice may occur, requiring caution. Kidney function may suddenly deteriorate, necessitating regular kidney function tests; discontinue the medication if abnormalities occur. Fungal infections such as oral candidiasis may appear. Vitamin K deficiency may lead to bleeding tendencies, so be mindful of bleeding symptoms. Symptoms such as headaches, general malaise, and upper abdominal discomfort may also occur. When using this medication, it's important to only take it for an appropriate duration to prevent the development of resistant bacteria. Thorough history taking and skin response tests are recommended before use to prevent severe allergic reactions. Be prepared for emergencies by having first aid available and monitor the patient in a stable condition after taking the medication. Caution is required when taken with diuretics or aminoglycoside antibiotics as it may lead to increased kidney damage. During pregnancy, its safety is not established; it should only be used when the benefits outweigh the risks. This drug can be passed through breast milk, so nursing women should use it cautiously. Safety has not been established in newborns and premature infants, and it is advisable not to use it in infants under 9 months. Elderly individuals should be cautious as decreased body function may lead to an increased incidence of adverse reactions, adjusting the dosage and administration intervals as necessary.

• shivering
• discomfort
• dysgeusia
• wheezing
• dizziness
• diarrhea
• tinnitus
• sweating
• rash
• urticaria

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. It is recommended to maintain a storage temperature between 1-degree and 30-degree Celsius. Proper storage will help preserve the effectiveness and safety of the medication.

Appearance

A hard capsule with light yellowish color on the lower part and light red color on the upper part, containing white to light yellow powder

Package unit

30 capsules, 300 capsules