Cefacline Capsule (Cefaclor Hydrate)

Adult dosage

For cefaclor hydrate, administer 250mg (potency) every 8 hours orally. In severe infections (such as pneumonia) and infections with low susceptibility, the dosage may be doubled. In cases of acute gonococcal urethritis, administer 3g of this drug combined with 1g of probenecid as a single dose.

Children's dosage

Administer 20mg (potency) per kg of body weight every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, a dose of 40mg (potency) per kg of body weight may be used, with a maximum dose of

This medication should not be used in patients who have experienced severe allergic reactions or shock after taking this drug or similar class antibiotics in the past. It contains lactose, so it should not be administered to patients with a genetic disorder that affects lactose digestion. Caution is advised for individuals allergic to penicillin or with a family history of such allergies, as well as for those prone to asthma or allergic skin reactions. Patients with severely impaired renal function, those unable to take oral medications, and the elderly should be closely monitored due to the risk of vitamin K deficiency symptoms. Patients with a history of gastrointestinal disorders should also be cautious when taking this medication. Rarely, serious side effects such as shock, anaphylaxis, skin rash, blood abnormalities, hepatitis, renal abnormalities, gastrointestinal disturbances, pneumonia, and central nervous system disorders may occur; if symptoms arise, discontinue the medication immediately and seek appropriate treatment. To prevent antibiotic resistance, it is recommended to use the drug only for the minimum required duration based on susceptibility testing. Be careful of interactions when combining with other medications, especially probenecid, antacids, nephrotoxic drugs, anticoagulants, and oral contraceptives. Women who are pregnant or nursing should carefully consider the risks and benefits of using this medication and monitor any effects it may have on the infant during breastfeeding. Safety for neonates and children, especially those under 1 month old, has not been established; therefore, caution is warranted when administering the drug. The elderly are at higher risk of side effects due to decreased bodily function, so dosage and administration intervals should be adjusted, with careful monitoring. This medication may affect certain clinical test results, so inform the physician about its use when undergoing tests. In cases of overdose, symptoms such as nausea, vomiting, abdominal discomfort, and diarrhea may occur; immediate medical attention is required in such instances. This drug is an antibiotic that works by inhibiting bacterial cell wall synthesis.

Serious side effects

Hives, swelling, difficulty breathing, shock, anaphylactic symptoms, Stevens-Johnson syndrome, toxic epidermal necrolysis, agranulocytosis, pancytopenia, aplastic anemia, hemolytic anemia, jaundice, acute renal failure, acute kidney injury, pseudomembranous colitis, severe colitis, interstitial pneumonia, eosinophilic pulmonary infiltrates, asthma attacks, confusion, severe headache, hallucinations, seizures, altered consciousness, vision changes, paralysis, severe systemic reactions accompanied by hypertension

Mild side effects

• Generalized flushing
• angioedema
• sensory disturbances
• fainting
• hypertension
• vasodilation
• rash
• erythema
• pruritus
• fever

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Furthermore, it should be kept at a normal room temperature between 1 and 30 degrees Celsius, avoiding excessively hot or cold locations.

Appearance

A hard capsule with a blue opaque upper part and a white opaque lower part filled with a pale yellow powder

Package unit

30 capsules/bottle, 300 capsules/bottle