Rabepra 20mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Administer 10 mg orally once daily for adults, with the possibility of increasing the dosage to 20 mg once daily depending on symptoms. The treatment duration is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If symptoms do not resolve after 8 weeks, consider administering 10 mg or 20 mg orally twice daily for an additional 8 weeks.

This medication should not be used in patients with allergies to specific ingredients or a history of hypersensitivity reactions. It is particularly contraindicated in patients allergic to penicillin-type or macrolide antibiotics, and in those taking certain heart-related medications. Pregnant or breastfeeding women should not use this medication. Patients with impaired liver function or the elderly should use this medication with caution, and those with a history of drug allergies should be closely monitored. If symptoms of allergy such as rash, hives, or itching occur while taking this medication, discontinue use immediately. Regular blood tests are recommended as changes in red or white blood cell counts may occur. Regular liver function tests should also be conducted, and if any liver function abnormalities or symptoms of jaundice appear, the medication should be discontinued. Caution is advised as symptoms related to the heart or changes in blood pressure, headaches, and neurogenic symptoms such as dizziness may occur. Gastrointestinal symptoms include diarrhea, abdominal pain, nausea, and vomiting, and if severe, immediate consultation with healthcare professionals is necessary. Respiratory symptoms may include cough and shortness of breath, and if symptoms are severe, the medication should be discontinued. Muscle pain, joint pain, skin rashes, and hair loss have also been reported, requiring careful observation if such symptoms arise. Long-term use of this medication may increase the risk of osteoporosis and fractures, so bone density testing is recommended if necessary. Regular monitoring of serum magnesium levels is needed as hypomagnesemia may occur with prolonged use. This medication inhibits gastric acid secretion, which may slightly increase the risk of bacterial infections in the gastrointestinal tract, so inform healthcare professionals if diarrhea persists. Caution is necessary while driving or operating machinery due to possible drowsiness or dizziness. There may be interactions with other medications, so consult a doctor or pharmacist if taking antibiotics, anticoagulants, antifungals, or antivirals. This medication should not be chewed or crushed and should be swallowed whole, stored out of reach of children. It is safest not to use this medication during pregnancy or breastfeeding, and care should be taken when administering to the elderly due to the potential for liver dysfunction. There is no specific antidote for overdose; treatment and supportive therapy should be administered according to symptoms.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, difficulty or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, vision changes, paralysis, urination

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius. This will help maintain the effectiveness and safety of the medication.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP packaging x 2), 28 tablets (14 tablets/Alu Alu packaging x 2)