Rabepara Tablet 10 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Typically, 10 mg is administered orally once daily; depending on symptoms, 20 mg may be administered orally once daily. Treatment duration is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg is administered orally once daily for 4 to 8 weeks. If symptoms do not resolve, an additional 8 weeks of 10 mg or 20 mg may be administered orally twice daily. For gastrointestinal reflux disease symptom relief: 10 mg is administered once daily. If symptoms do not control after 4 weeks, further medical consultation is needed. Once symptoms are resolved, on-demand therapy can be used to manage subsequent symptoms with 10 mg administered orally once daily. For long-term maintenance therapy of gastroesophageal reflux disease: 10 mg or 20 mg may be administered orally once daily, depending on the patient. For Helicobacter pylori eradication: Patients infected with Helicobacter pylori should receive eradication therapy. It is recommended to combine this medication at 20 mg with clarithromycin 500 mg and amoxicillin 1 g, administered orally twice daily for 7 days. For Zollinger-Ellison syndrome: The recommended starting dose for adults is 60 mg once daily, and the dose can be adjusted up to 120 mg once daily according to individual patient needs. Doses of up to 100 mg can be given once daily, and doses of 120 mg should be divided into two doses of 60 mg administered daily. Experience has shown Zollinger-Ellison syndrome patients have received this medication for up to 1 year. Patients with liver dysfunction: Adverse reactions of hepatic encephalopathy have been reported in cirrhotic patients, thus should be administered with caution. For pediatric patients: Safety has not been established. For elderly patients: Caution is advised due to possible reduced liver function.

This medication should not be used in patients with allergies to certain components or a history of hypersensitivity reactions. In particular, caution is required for those allergic to penicillins or macrolide antibiotics. It should also not be administered to patients taking certain heart-related medications or to pregnant or breastfeeding women. Patients with reduced liver function, elderly patients, and those with a history of drug allergies should use it cautiously. If any allergic symptoms such as skin rash or itching occur while taking this medication, discontinue it immediately. Regular blood tests are required as there may be changes in red or white blood cell counts. Liver function tests should also be conducted regularly, and if symptoms of hepatitis or jaundice occur, usage should be suspended. Rarely, heart-related side effects may occur, so symptoms such as dizziness or chest pain should be monitored. Digestive symptoms including diarrhea, abdominal pain, and nausea may occur, and in severe cases, medical consultation is required. Mental symptoms such as headache, insomnia, and anxiety may occur, so consult a specialist if symptoms are severe. Various adverse reactions such as respiratory issues, muscle pain, and skin rashes have been reported, so report any unusual symptoms. Long-term use of this medication may increase the risk of bone fractures, so caution is advised during prolonged treatment. Additionally, hypomagnesemia may occur, so magnesium levels should be checked periodically if needed. Suppression of gastric acid secretion may slightly increase the risk of bacterial infections in the stomach, so consult a doctor if diarrhea persists. Caution is advised when driving or operating machinery as drowsiness may occur. There may be interactions with other medications, so it is essential to inform your healthcare provider about any medications you are currently taking. It is safest to avoid use during pregnancy or breastfeeding. Safety in pediatric patients has not been established, so use is not recommended. In case of overdose, as there is no specific antidote, immediate medical attention is required. The medication should be swallowed whole and not chewed or crushed, and stored out of the reach of children. If there are suspicions of gastrointestinal diseases or malignant tumors, it should be used only after an accurate diagnosis, and regular check-ups are necessary for long-term use.

Serious side effects

• Urticaria
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweats
• pallor
• fulminant hepatitis
• liver dysfunction
• jaundice
• severe rash with fever

Mild side effects

• Occasionally
• rashes
• itching
• reduced red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia

This medication must be stored in a tightly sealed container to protect it from exposure to air and moisture. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius to preserve the medication's effectiveness and safety.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP packaging x 2), 28 tablets (14 tablets/Alu Alu packaging x 2)