Medication info

Crabactor 500 mg (Levofloxacin Hydrate)

Prescription medicationApproval withdrawn
Ingredient · strength
Levofloxacin Hydrate›Strength being verified
Manufacturer / importer
이연제약(주)
Appearance
Pink rectangular film-coated tablet
Packaging
28 tablets/bottle, 100 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 201902288 · Approved 2019.04.15

This product's status changed to Approval withdrawn on 2023.05.26. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.
Who uses it
Adults
Adult dosage
Generally, for adult levofloxacin, it is administered orally once daily at 250-750 mg. For patients with normal kidney function (creatinine clearance over 80 mL/min): - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10-14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: for 7 days - Acute sinusitis: for 10-14 days - Chronic

Ingredients

Manufacturer
이연제약(주)

Efficacy & effects

Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary tract infections
  • uncomplicated urinary tract infections
View approved original text

This drug is an antibiotic effective against various bacteria, used to treat skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, chronic bacterial prostatitis, and various urinary tract infections. As a fluoroquinolone, it carries a risk of serious side effects, so it is used when no other treatment options are available for the aforementioned diseases. Therefore, this drug is cautiously applied in the treatment of complicated infections to effectively improve patients' symptoms.

Dosage and Administration

Adult dosage

Generally, for adult levofloxacin, it is administered orally once daily at 250-750 mg. For patients with normal kidney function (creatinine clearance over 80 mL/min): - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10-14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: for 7 days - Acute sinusitis: for 10-14 days - Chronic

Precautions

This drug can cause problems with tendons such as tendonitis and tendon rupture, and if these symptoms occur, use should be discontinued immediately. It may also affect peripheral neuropathy and the central nervous system, so caution is necessary if neurological symptoms appear. Patients with myasthenia gravis may experience worsened symptoms, so this medication should not be used. This drug is only used for specific infections and is safe to administer only when no other treatment methods are available. The risk of tendon rupture is higher in the elderly, patients with poor kidney function, and those taking corticosteroids together. Therefore, it is advisable to avoid concurrent use with corticosteroids, and if pain or inflammation occurs, the medication should be discontinued immediately. Due to the risk of seizures, patients with epilepsy or a history of seizures should use this drug with caution. Patients with allergies to similar medications or a history of tendonitis or tendon rupture, children and adolescents in the growth phase, pregnant or nursing women should not use this drug. Additionally, patients with certain genetic disorders such as lactose intolerance should avoid administration. During medication, severe allergic reactions, skin rashes, photosensitivity reactions, neurological symptoms may occur; if such symptoms appear, consult a doctor immediately. Care should be taken while driving or operating machinery due to risks of dizziness and drowsiness. This drug can affect blood sugar control, so diabetic patients should frequently monitor their blood sugar levels, and if hypoglycemic symptoms occur, they should stop taking the drug and seek treatment immediately. In case of an overdose, central nervous system symptoms and cardiac abnormalities may occur, so appropriate treatment in a medical facility should be sought immediately. Women who are pregnant or of childbearing potential, and nursing women should not use this drug and should discontinue nursing if necessary. This drug is not administered to children and adolescents due to the risk of joint and cartilage damage. Elderly patients may have increased drug concentrations due to decreased kidney function, requiring dosage adjustment and caution. During treatment, strong sunlight or artificial ultraviolet exposure should be avoided, and if any unusual symptoms occur, medical advice should be sought immediately.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory problems with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Nausea
  • diarrhea
  • vaginitis
  • insomnia
  • abdominal pain
  • bloating
  • itching
  • dizziness
  • rash
  • indigestion
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  • stomatitis
  • glossitis
  • thirst
  • constipation
  • headache
  • neurosis
  • erythematous rash
  • drowsiness
  • excitement
  • dry mouth
  • tremor
  • allergic reactions
  • palpitations
  • elevated BUN
  • elevated serum creatinine
  • elevated liver enzymes
  • elevated ALP
  • elevated γ-GTP
  • elevated total bilirubin
  • leukopenia
  • anemia
  • decreased hemoglobin
  • hematocrit

Not everyone experiences these, and they can vary from person to person.

Storage

This drug is sensitive to air and moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature of 1 to 30 degrees Celsius room temperature to preserve the efficacy of the medication for a long time.

Appearance and packaging

Appearance

Pink rectangular film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.