SAMSUNG Clarithromycin Tablet 250mg

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this drug twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Helicobacter pylori eradication in patients with duodenal ulcers: Administer 500mg (potency) of this drug three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years of age and older: Same as adults Children under 12 years of age: Use clarithromycin dry syrup.

This drug should not be used in patients who are allergic to certain ingredients or have hypersensitivity to specific antibiotic classes. Additionally, caution should be taken when administering to patients taking certain heart-related medications due to the risk of cardiac arrhythmias, and concomitant use should be avoided. In patients with severely impaired liver or kidney function, the use of this medication may be restricted or dosage adjustment may be necessary. It is safer not to administer this medication to pregnant or breastfeeding women. Special care should be taken when administering to children and the elderly, and the safety for children under 12 years has not been fully established. This drug can interact with various medications; therefore, patients taking other medications should consult their physician or pharmacist. During administration, patients should be closely monitored for allergic reactions, gastrointestinal disturbances, liver dysfunction, kidney dysfunction, and cardiac symptoms. If any unusual symptoms occur, administration should be immediately stopped, and medical consultation sought. Prolonged or high-dose administration may cause hearing impairment or tinnitus, and care should be taken. Patients should report any persistent gastrointestinal symptoms such as diarrhea to their healthcare provider immediately. In cases of overdose, emergency measures such as gastric lavage may be necessary, and hemodialysis or peritoneal dialysis may not be effective. This medication may affect driving or operating machinery, so caution is advised during its use. To prevent the occurrence of antibiotic resistance, it should only be taken for the prescribed duration as directed by a physician.

Shock, anaphylactic symptoms, difficulty breathing, convulsions, redness, rash, itching, hives, skin redness, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, convulsion type, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste alteration, loss of appetite, constipation, discoloration of stool, membranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute sinusitis exacerbation, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, loss of appetite, dark-colored urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, fatigue, elevated CPK, elevated serum myoglobin, elevated urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbances, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea nitrogen, intravenous injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase, elevated lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, cardiac arrest, atrial fibrillation, ectopic beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, burping, distension, tongue discoloration, tooth discoloration, rash, hyperhidrosis, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, it should be stored at room temperature between 15 to 30 degrees Celsius.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 200 tablets/bottle