Medication info
Levofine Tablet 500mg (Levofloxacin Hydrate)

Levofine Tablet 500mg (Levofloxacin Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›512.3mg / 1 tablet
Manufacturer / importer
(주)휴온스
Appearance
Peach-colored oblong film-coated tablet
Packaging
28 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201902152 · Approved 2019.04.09

Summary

Main use
Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.
Who takes it
Adults
Adult dose
Typically, for adults, Levofloxacin is administered orally at a dose of 250 to 750 mg once daily. 1. For patients with normal kidney function (creatinine clearance greater than 80 mL/min) - Complicated skin and soft tissue infections: 750 mg at 24-hour intervals for 10 to 14 days - Community-acquired pneumonia: 500 mg at 24-hour intervals for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10 to 14 days

Ingredients

Manufacturer
(주)휴온스

Efficacy & effects

Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary tract infections
  • uncomplicated urinary tract infections
View approved original text

This drug is effective against various bacteria including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli, and Pseudomonas aeruginosa. It is mainly used for the treatment of complicated skin and soft tissue infections, pneumonia occurring in the community, acute bacterial exacerbations of chronic bronchitis, acute sinusitis, chronic bacterial prostatitis, and various types of urinary tract infections. However, this drug is a fluoroquinolone antibiotic and should only be used when no other treatment options are available, due to the potential for severe side effects. It is important to take the medication exactly as prescribed by a doctor for effective treatment. This drug is used for the treatment of infections caused by various bacteria.

How to take

Adult dose

Typically, for adults, Levofloxacin is administered orally at a dose of 250 to 750 mg once daily. 1. For patients with normal kidney function (creatinine clearance greater than 80 mL/min) - Complicated skin and soft tissue infections: 750 mg at 24-hour intervals for 10 to 14 days - Community-acquired pneumonia: 500 mg at 24-hour intervals for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10 to 14 days

Precautions

This drug is a fluoroquinolone antibiotic used for the treatment of certain bacterial infections. Caution should be taken when taking this medication as serious side effects such as tendon problems like tendonitis or tendon rupture, peripheral neuropathy, central nervous system adverse reactions, and exacerbation of myasthenia gravis may occur. If any of these symptoms appear, stop taking the medication immediately and consult a physician. Patients with a history of myasthenia gravis should not take this medication. This drug is used only when there are no other treatment options available for certain infections such as acute bacterial sinusitis, acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease, uncomplicated urinary tract infections, and acute otitis media. Elderly patients, patients with impaired kidney function, solid organ transplant recipients, and those taking corticosteroids are at increased risk of tendon rupture and should be monitored closely. Co-administration with corticosteroids should be avoided, and if symptoms of pain, inflammation, or tendon rupture appear, the medication should be stopped immediately. This drug may affect the central nervous system, increasing the risk of seizures; therefore, caution should be exercised when prescribing to patients with epilepsy or cerebrovascular disorders. Additionally, this drug can cause certain allergic reactions or severe skin reactions, and if these symptoms occur, the medication should be stopped immediately and the healthcare provider consulted. Women who are pregnant or may become pregnant, nursing mothers, adolescents under the age of 18, patients with epilepsy, and those with lactose intolerance should not take this medication. This drug may interact with certain other medications, so it is essential to inform the physician or pharmacist if taking other drugs. During treatment, avoid strong sunlight or artificial ultraviolet exposure, and caution is required when driving or operating machinery as dizziness or drowsiness may occur. Diabetic patients taking blood glucose control medications should be vigilant about fluctuations in blood sugar and check their levels regularly. In the case of overdose, central nervous system symptoms and heart abnormalities may occur, and immediate medical attention should be sought. This medication is excreted through the kidneys, thus patients with diminished kidney function should have their dosage adjusted and be monitored. Overall, this drug may have serious side effects, so it is crucial to take it exactly as directed by a physician and consult healthcare professionals immediately if any unusual symptoms appear.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, shock, hypotension, respiratory distress, feelings of chest oppression, severe allergic reactions, severe skin adverse reactions: rash, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions: Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), respiratory issues: fever, difficulty breathing

Mild side effects

  • Insomnia
  • dizziness
  • headache
  • tremors
  • anxiety
  • depression
  • hallucinations
  • paranoia
  • irritability
  • delirium
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  • disorientation
  • attention deficit
  • nightmares
  • sleep disorders
  • suicidal thoughts
  • restlessness
  • confusion
  • visual and auditory disturbances
  • taste and smell disorders
  • tinnitus
  • sensory disturbances
  • sensory loss
  • weakness
  • palpitations
  • QT interval prolongation
  • arrhythmia
  • increased BUN and serum creatinine
  • nausea
  • vomiting
  • abdominal discomfort
  • diarrhea
  • loss of appetite

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain the storage temperature between 1 to 30 degrees Celsius. This will help preserve the drug's effectiveness and safety over time.

Appearance and packaging

Appearance

Peach-colored oblong film-coated tablet

Package unit

28 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.