Monarin Tablets 0.1 mg (Desmopressin Acetate)

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) : Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after determining the dose. Treatment initiation with this medicine is not recommended in patients aged 65 years or older. In elderly patients who require treatment, closely monitor serum sodium levels, etc. (See 5. General Precautions under Precautions for Use.)

Child dose

Primary nocturnal enuresis (5 years of age and older) : Administer desmopressin acetate 0.2mg orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following a treatment-free period of at least 1 week.

This medication helps regulate the body's fluid balance. When taking this medication, you should drink water only as much as you feel thirsty, as excessive fluid intake can lead to severe hyponatremia or fluid overload, causing serious coma. Patients with allergies to this medication or with specific kidney diseases, heart failure, or habitual nocturia should not take it. Additionally, this medication should only be used for nocturia patients with normal blood pressure, and those with specific genetic issues such as lactose intolerance should also avoid taking it. Patients with hypertension, cardiovascular diseases, chronic kidney disease, pregnant women, children, and the elderly, as well as those at risk of electrolyte imbalance, should use this medication cautiously. During treatment, serious side effects such as weight gain, headache, coma, and seizures may occur, so if these symptoms appear, you should consult a doctor immediately. Fluid intake should be restricted from 1 hour before taking this medication to 8 hours after, and should be more strictly limited for those with impaired kidney function. Individuals over 65 years of age are at increased risk for developing hyponatremia, so sodium levels should be monitored regularly from their blood. Additionally, before taking this medication, it is necessary to record the frequency and amount of urination for at least two days to accurately assess the severity of nocturia. If dehydration or electrolyte imbalances are expected due to acute infections, fever, gastrointestinal inflammation, etc., this medication should be discontinued. This medication does not affect your ability to drive or operate machinery. This medication may interact with other drugs, so care should be taken when used with tricyclic antidepressants, diuretics, corticosteroids, non-steroidal anti-inflammatory drugs, and sodium levels and fluid status should be monitored regularly. During pregnancy, it should only be used when necessary due to the risk of uterine contractions, and breastfeeding should be discontinued as the drug may pass into breast milk.

• coma
• convulsions
• weight gain
• hyponatremia
• emotional disturbances
• headache
• abdominal pain
• nausea
• allergic skin reactions
• dizziness

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and it is recommended to store it at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication.

Appearance

White oval tablet

Package unit

30 tablets/bottle