Rosuvastatin Calcium 5 mg Tablets

Adult dosage

This medication can be administered once daily at an initial dose of 5 milligrams, without regard to meals. If more reduction in LDL-cholesterol is needed, the maintenance dose should be adjusted, and most patients are controlled at a maintenance dose of 10 milligrams once daily. The maintenance dose can be adjusted according to LDL-cholesterol levels, treatment goals, and patient response, typically at intervals of 4 weeks or more, with a maximum of 20 milligrams per day.

Children's dosage

For pediatric patients with familial hypercholesterolemia (ages 10 to 17), the dosage range is once daily from 5 milligrams to 20 milligrams. The dosage should be adjusted individually based on recommended treatment goals over a 4-week period.

This medication should not be used in certain patients. For instance, it should not be given to those with allergies to its components, unexplained liver dysfunction, muscle diseases, or severe renal impairment. Pregnant or nursing women, as well as fertile women who do not use appropriate contraception, are also advised against using this medication. Additionally, high doses should be avoided in patients prone to muscle diseases. This medication should be used cautiously in patients with poor liver function or those consuming excessive alcohol, and liver function tests should be repeated before and during treatment. If symptoms such as muscle pain or weakness appear, medical personnel should be informed immediately, and blood tests may be necessary to assess muscle damage. This medication can rarely cause severe skin reactions, liver damage, and muscle damage, so discontinuation is essential if such symptoms arise. Interactions may occur when taken with other medications, particularly certain antiviral agents, immunosuppressants, and fibrates, so caution is warranted. Pregnant or nursing women should not use this medication, and women of childbearing potential should use appropriate contraception. In case of overdose, there is no specific antidote; therefore, treatment should align with symptoms while monitoring liver function and muscle enzyme levels. This medication is not known to significantly affect driving or machine operation, but caution is necessary as dizziness may occur. Finally, regular check-ups and consultations with healthcare personnel are important for safe treatment while taking this medication.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, hepatic failure, severe edema, chest tightness, difficulty breathing, respiratory distress, severe muscle weakness, oculomotor weakness, immune-mediated necrotizing myopathy, rhabdomyolysis, thrombocytopenia, acute kidney failure, oliguria

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, rash, myalgia, weakness, cough, diarrhea, hematuria, fatigue, numbness, paresthesia, discomfort in the chest, loss of appetite, abdominal bloating, fainting, generalized pain, muscle cramps, gout, erectile dysfunction, joint pain, depression, sleep disturbances (including insomnia and nightmares), sexual dysfunction, gynecomastia, memory decline, forgetfulness, amnesia, memory impairment, confusion

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is recommended to store it at room temperature between 1°C and 30°C. By storing it this way, the efficacy of the medication can be maintained and deterioration prevented.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle