Curamus Duo Dry Syrup [Amoxicillin-Potassium Clavulanate (7:1)]

Adult dose

For recurrent tonsillitis and other upper respiratory infections, lower respiratory infections, urinary tract infections, and mild to moderate skin and soft tissue infections, take amoxicillin/potassium clavulanate 25 mg/3.6 mg per kg of body weight per day divided into two doses. For severe infections such as otitis media, sinusitis, and lower respiratory infections such as bronchopneumonia and urinary tract infections, take amoxicillin/potassium clavulanate 45 mg/6.4 mg per kg of body weight per day.

Child dose

The 7:1 syrup is not suitable for patients under 2 months of age. It is not appropriate for pediatric patients with renal failure.

This medicine contains the artificial sweetener aspartame, so it should not be used by patients with phenylketonuria. The intake of aspartame should be limited to below the WHO recommended levels, with a maximum dose of 2.4 grams per day for the average adult. It should not be administered to patients with allergic reactions to this medication or beta-lactam antibiotics, those with infectious mononucleosis or lymphocytic leukemia, patients with liver impairment or a history of jaundice, or those with lactose intolerance or certain genetic digestive disorders. Caution is advised in patients with impaired liver function or moderate to severe kidney impairment, those with allergic constitutions, patients for whom oral intake is difficult, the elderly, patients in poor general condition, and those with gastrointestinal diseases due to vomiting or diarrhea. During treatment, gastrointestinal symptoms such as diarrhea, dyspepsia, vomiting, and abdominal pain may occur, so attention is needed, and immediate medical attention should be sought if any allergic reactions such as liver dysfunction, skin rashes, or respiratory difficulties appear. It is recommended to administer this medication only for the necessary minimum duration to prevent the emergence of resistant bacteria, and patients with hypersensitivity to penicillin drugs should be particularly cautious. Close observation of the patient should be conducted after administration due to the risk of acute allergic reactions. Severe gastrointestinal diseases such as pseudomembranous colitis may occur, so if there is severe diarrhea or abdominal cramping, treatment should be discontinued immediately and the patient should be taken to the hospital. During prolonged administration, regular checks of liver function, kidney function, and blood status should be conducted, and a thorough history of allergies should be confirmed before administering the medication. This medication should be stored in the refrigerator and should be finished within 7 days after preparation. Additionally, since this medication may interact with other drugs, it is essential to inform the healthcare provider of any other medications being taken. Women who are pregnant or breastfeeding should use this medication cautiously after consulting with a doctor, and it is particularly advisable to avoid use during the first three months of pregnancy. It is preferable not to use this medication in children, especially newborns or premature infants under 2 months of age, as safety has not been established. Elderly patients may experience adverse reactions more easily due to decreased bodily functions, so the dosage and intervals should be adjusted, and careful monitoring is necessary. In case of overdose, gastrointestinal symptoms, kidney dysfunction, or allergic reactions may occur, so treatment should be stopped immediately and appropriate medical attention should be sought.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, mucocutaneous syndrome (Stevens-Johnson syndrome), shock, anaphylaxis, angioedema, anaphylactic shock, high fever with severe rash, blisters, exfoliation of skin, pain in mucous membranes of mouth/eyes, cholestatic jaundice, hepatitis, liver dysfunction (jaundice), sudden and severe headache, seizures, confusion, visual disturbances, paralysis, blood disorder

Mild side effects

Diarrhea, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, gastric acidity, loose stools, dry mouth, bloody stools, candidiasis, antibiotic-associated colitis, itching, erythema multiforme, dermatitis, serum sickness-like symptoms (fever, rash, joint pain, swelling, lymphadenopathy), eosinophilia, acute generalized exanthematous pustulosis, dyspnea associated with bronchospasm, laryngeal edema

This medication should be stored in a tightly sealed container to protect it from air and moisture, in a cool place between 1 and 25 degrees Celsius. Storing it this way helps maintain the drug's efficacy for a longer period.

Appearance

A whitish powder with a peculiar smell, a syrup that is dissolved before use

Package unit

50mL/bottle, 500mL/bottle