Medication info
Carbeta Tablet 25 Milligrams (Carvedilol)

Carbeta Tablet 25 Milligrams (Carvedilol)

Prescription medicationTabletOral
Ingredient · strength
Carvedilol›25mg / 1 tablet
Manufacturer / importer
HLB Pharma Co., Ltd.
Appearance
White round tablet
Packaging
90 tablets (10 tablets/PTP × 9)
Approval status
Active

MFDS item code 201805248 · Approved 2018.12.26 · Insurance code 647303580

Summary

Main use
Treatment of essential hypertension, adjunctive treatment of congestive heart failure, and treatment of chronic stable angina
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may provide an adequate effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, take 12.5 mg of this medicine orally twice daily, then take 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient should be stable on the standard treatment regimen already being used (the conventional treatment regimen for chronic heart failure, which includes an ACE inhibitor, a diuretic, and usually a digitalis preparation). Fluid retention should also be minimized before starting treatment with this medicine. 1) The initial dose is generally 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the dose the patient can tolerate. 3) The effective minimum dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To regulate the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows absorption and may reduce the incidence of orthostatic hypotension.

Ingredients

Manufacturer
HLB Pharma Co., Ltd.

Efficacy & effects

Treatment of essential hypertension, adjunctive treatment of congestive heart failure, and treatment of chronic stable angina

  • Essential hypertension
  • chronic stable angina
  • congestive heart failure
View approved original text

This medication is used in the treatment of cardiovascular diseases such as essential hypertension, chronic stable angina, and congestive heart failure. It is particularly effective when given as adjunct therapy with diuretics, digitalis preparations, ACE inhibitors, and other vasodilators. By doing so, it helps control blood pressure and reduces the burden on the heart to improve symptoms. It supports your heart health and assists in enhancing therapeutic results.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may provide an adequate effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, take 12.5 mg of this medicine orally twice daily, then take 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient should be stable on the standard treatment regimen already being used (the conventional treatment regimen for chronic heart failure, which includes an ACE inhibitor, a diuretic, and usually a digitalis preparation). Fluid retention should also be minimized before starting treatment with this medicine. 1) The initial dose is generally 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the dose the patient can tolerate. 3) The effective minimum dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To regulate the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows absorption and may reduce the incidence of orthostatic hypotension.

Precautions

This medication should not be administered to certain patients. For instance, patients who are allergic to this drug or its components, those with severely impaired heart function, those with a slow heart rate or problems with heart conduction, those with pulmonary-related heart diseases, patients with metabolic issues due to diabetes, and those with asthma or chronic obstructive pulmonary disease may be at risk of worsening symptoms from using this medication. Additionally, it is safer for pregnant or breastfeeding women not to take this medication as it may cause side effects in the fetus or newborn and can be transmitted through breast milk. While taking this medication, blood pressure and heart function should be monitored regularly, and if symptoms of bradycardia (slow heart rate) or hypotension appear, the dosage may need to be reduced or discontinued. Abrupt cessation can worsen heart-related symptoms, so dosage should be gradually reduced under a physician's guidance. This drug can influence blood sugar control, so patients with diabetes should frequently check their blood sugar levels. Also, caution is needed for patients with impaired kidney or liver function, as renal function can occasionally deteriorate, necessitating regular monitoring. This medication can interact with various drugs, so if you are on other medications, you must consult with your doctor or pharmacist. The risk of side effects may increase when taken with antihypertensives, antidepressants, anti-arrhythmics, insulin, hypoglycemic agents, anesthetics, alcohol, etc. If symptoms such as dizziness, drowsiness, irregular heartbeat, difficulty breathing, or severe allergic reactions occur, promptly inform healthcare professionals. The safety and efficacy of this medication in children and adolescents have not been established; therefore, it is advisable not to use it in individuals under the age of 18. In the elderly, drug concentrations may increase due to decreased liver function, and there is a risk of stroke from blood pressure lowering, so they should start at a low dose and use it cautiously. Lastly, overdose of this medication can result in serious heart problems, difficulty breathing, and consciousness disturbances, so it is crucial to adhere strictly to the prescribed dosage, and if an overdose is suspected, immediately contact a healthcare facility for appropriate treatment.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucinations
  • confusion
  • depression
  • sleep disorders
  • nightmares
  • psychosis
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  • severe bradycardia
  • shock
  • complete heart block
  • heart failure
  • cardiac arrest
  • hypotension
  • loss of consciousness
  • decreased pulse rate
  • cold extremities
  • edema
  • cardiac arrest
  • renal function worsening
  • renal failure
  • increased airway resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichenoid reactions
  • sweating
  • allergic rash
  • serum aminotransferase changes
  • thrombocytopenia
  • leukopenia
  • hypoglycemia
  • latent hyperthyroidism
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension in angina patients
  • liver dysfunction
  • jaundice
  • limb pain
  • decreased tearing
  • sensory disturbances
  • visual disturbances
  • eye irritation
  • dry mouth
  • urinary disorders
  • sexual dysfunction
  • allergic reactions
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • hypotension
  • bradycardia
  • myocardial weakness
  • cardiogenic shock
  • cardiac arrest
  • dyspnea
  • bronchospasm
  • vomiting
  • consciousness disturbance
  • generalized seizures

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container protected from light, and keep it at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the drug's efficacy for a longer time.

Appearance and packaging

Appearance

White round tablet

Package unit

90 tablets (10 tablets/PTP × 9)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.